Pseudomonas aeruginosa pyoverdine maturation enzyme PvdP has a noncanonical domain architecture and affords insight into a new subclass of tyrosinases [Enzymology]

In conclusion, our work unravels the structural basis of PvdP's activity in PVD biosynthesis, observations that may inform structure-guided development of PvdP-specific inhibitors to manage P. aeruginosa infections.

Source: Journal of Biological Chemistry - September 21, 2018 Category: Chemistry Authors: Juliane Poppe, Joachim Reichelt, Wulf Blankenfeldt Tags: Editors ' Picks Source Type: research