Ultra structural observations of anti-leishmanial effects of new synthetic 3-imidazolylflavanoneson Leishmania majorusing scanning electron and atomic force microscopes.

CONCLUSION: Our results strongly confirm the Leishmania cell wall as a potent target for the new synthesized azole (IF-2). Accordingly, focus on membrane integrity and glycoconjugates of Leishmania parasite to design new therapeutic agents is recommended. PMID: 30227826 [PubMed - as supplied by publisher]
Source: Recent Patents on Anti-Infective Drug Discovery - Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research