Bisphosphonates and Osteonecrosis
Bisphosphonates are medications commonly used to treat primary and metastatic bone cancer, as well as osteoporosis. A 47-year-old woman undergoing breast cancer treatment for 15 years, with bone metastasis diagnosed 5 years prior, was currently taking zoledronic acid (Zometa, Novartis), 4 mg, once monthly, and with a fractured tooth 15. An atraumatic extraction of teeth with immediate implant installation (Replace Select® 4.3 × 13 mm Nobel Biocare) was performed. After 2 years, the patient complained of pain, and there was remarkable bone loss around the tissues.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Lorrany De Barros Del Piero, Gabriela Tonon Da Costa Dondone, Paula Silva Braga, Alfredo Carlos Rodrigues Feitosa, Radolpho Matos Pereira Alves Rosa, Khalila Chequer Cotrim, Eduardo Cl áudio Lopes De Chaves E Mello Dias Tags: Oral and Maxillofacial Pathology Source Type: research
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