Investigational steroid mirrors prednisone's benefits while taming its side effects

(Children's National Health System) A head-to-head trial comparing the decades-old steroid, prednisone, and a promising new steroid, vamorolone, finds both act on the same key set of genetic pathways involved in controlling inflammation, indicates a new study led by Children's National Health System researchers. However, the study suggests the new investigational steroid doesn't activate several additional pathways involved in prednisone's bevy of undesirable side effects.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news