Overwhelming evidence shows hepatitis C treatment effective for people who inject drugs
(University of New South Wales) Researchers are calling on an end to discriminatory health and illicit drugs policies, based on overwhelming evidence that new hepatitis C therapies are effective at curing the virus in people who inject drugs.
Publication date: Available online 3 June 2020Source: Life SciencesAuthor(s): Na Fu, Huijuan Du, Dongdong Li, Yu Lu, Wencong Li, Yang Wang, Lingbo Kong, Jinghua Du, Suxian Zhao, Weiguang Ren, Fang Han, Rongqi Wang, Yuguo Zhang, Yuemin Nan
CONCLUSION: the proportion of admissions due to decompensated HCV-related cirrhosis has decreased by almost 30 % since the introduction of the DAA. In addition, the characteristics of patients admitted have changed since the application of interferon-free regimens. PMID: 32496126 [PubMed - as supplied by publisher]
CONCLUSIONS: This study showed that a no-limit reimbursement policy for DAAs prescriptions to HCV infected individuals in Italy widened the types of treated patients, but the process towards elimination of HCV infection was not significantly changed. PMID: 32495912 [PubMed - in process]
Authors: Ordak M, Nasierowski T, Pawlik K, Muszynska E, Bujalska-Zadrozny M Abstract Objectives: The purpose of this research was to investigate the effectiveness of the methadone programme in a group of patients taking mephedrone with heroin.Methods: The research involved 230 people who took part in the methadone programme between 2010 and 2019: 101 people on a mephedrone binge and taking heroin and 129 people addicted to heroin.Results: Number of re-hospitalisations was higher in a group of patients on a mephedrone binge taking heroin in comparison to heroin dependent patients (91.9 vs 79.8%, p
CONCLUSIONS: We identified risk behaviors among Alabama populations associated with increased odds for HIV and viral hepatitis co-infection. Outreach, prevention, testing, and treatment resources can be targeted to these populations. PMID: 32483640 [PubMed - in process]
CONCLUSIONS: We found that receiving the PREP-C assessment did not improve treatment outcomes, suggesting that targeted pretreatment assessment is unnecessary even in a medically and psychosocially complex population. PMID: 32483634 [PubMed - in process]
ConclusionsThe current study demonstrated that chronic HCV infection is significantly associated with a 1.94-fold increased risk of developing lung cancer. However, further studies are still needed to investigate if this association is causative.
A 66-year-old woman with Hepatitis C virus-related cirrhosis was referred to our institution for endoscopic management of large isolated gastric varies. She was recently admitted to another hospital for melena and hepatic encephalopathy. Esophagogastroduodenoscopy (EGD) during that hospitalization had shown large gastric varies without significant esophageal varies. Given no active bleeding was seen du ring endoscopy, no endoscopic intervention was performed, and she was conservatively managed with plans for outpatient follow-up after discharge.
This study aimed to analyze clinical and laboratory parameters and their association with long-term outcomes in patients who underwent liver transplantation for hepatocellular carcinoma treatment, according to the etiology of the underlying chronic liver disease, in order to identify predictors of response to this therapeutic modality. METHODS: Demographic, clinical, and laboratory data from a cohort of 134 patients who underwent orthotopic liver transplantation for hepatocellular carcinoma treatment at a referral center in Brazil were retrospectively selected and compared according to the etiologic group of the underlying...
Conclusion During every step of the retrieval chain, many patients were lost. Nevertheless, with substantial effort, we were able to identify, retrieve, and positively re-evaluate a limited number of individuals with a possible chronic HCV infection who were lost to medical follow-up (19 patients). With this case-finding approach, we were able to prevent potential severe complications in these patients and contribute to a small step in the eradication of HCV in the Netherlands.