KIR genotyping data of more than three million individuals are available for global unrelated stem cell donor searches (Comment to: Weisdorf D, Cooley S, Wang T, et al. KIR donor selection: feasibility in identifying better donors. Biol Blood Marrow Transplant. 2018; doi: 10.1016/j.bbmt.2018.08.022.)

Weisdorf et al. [1] report on the feasibility of optimized unrelated stem cell donor selection by donor KIR genotyping during ongoing donor searches. They identify core issues of this process – including participation of transplant centers, number of requested donors per search, donor availability for KIR genotyping, and coverage of KIR genotyping costs – and conclude that pre-search donor KIR genotyping would “accelerate the search process and provide useful data to provide the be st donors quickly”.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Source Type: research