Evidence for stress-induced bleeding in a patient with von Willebrand factor deficiency - Subramanian K, Pravallika M, Menon V.

Literature reveals that psychological stress is related to hemostatic mechanisms and that excess stress can lead to prothrombotic events. Patients with chronic bleeding disorders report increased levels of subjective distress. The psychobiological link bet...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

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Condition:   Bleeding Interventions:   Drug: Wilate;   Other: Placebo Sponsor:   University Hospital, Basel, Switzerland Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 19 September 2020Source: The Annals of Thoracic SurgeryAuthor(s): Jason M. Ali, Caroline Gerrard, James Clayton, Narain Moorjani
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
This article aims to provide advice on recognising patients at risk, and to discuss how to utilise key messages within published guidelines when making treatment decisions. The overall intent is to help primary care clinicians who are likely to encounter these patients more and more. PMID: 32940591 [PubMed - in process]
Source: Primary dental care : journal of the Faculty of General Dental Practitioners UK - Category: Dentistry Tags: Prim Dent J Source Type: research
Condition:   Bleeding Interventions:   Drug: Wilate;   Other: Placebo Sponsor:   University Hospital, Basel, Switzerland Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusion: Laparoscopic surgery with NOSE for eligible patients with CRC was a feasible choice. PMID: 32940092 [PubMed - as supplied by publisher]
Source: Minimally Invasive Therapy and Allied Technologies - Category: Surgery Tags: Minim Invasive Ther Allied Technol Source Type: research
This article aims to review pediatric PTH, its epidemiology and pathophysiology with a focus on management and future directions.Recent FindingsUsing MEDLINE, EMBASE, 52 articles on PTH in children and adolescents from 2016 to 2020 were identified. Over the last 4  years, our understanding of traumatic brain injury pathophysiology has grown, expanding the potential for more therapeutic targets. Despite this achievement, and recently published consensus guidelines, the review demonstrated a lack of published controlled trials to help guide management of pedia tric PTH.SummaryThe last 4  years have provided new ins...
Source: Current Neurology and Neuroscience Reports - Category: Neuroscience Source Type: research
Transcatheter Aortic Valve Implantation (TAVI) is increasingly being performed in patients with severe aortic stenosis1. The current American guidelines recommend dual antiplatelet therapy (DAPT) for the first 3 to 6 months after TAVI in patients who are not on anticoagulation1. These recommendations have been established based on experts ’ opinions due to the lack of clinical trials investigating the optimal antithrombotic therapy in this population. More recently, multiple studies have questioned the benefit of DAPT in reducing thromboembolic outcomes and revealed high bleeding events in patients who received DAPT ...
Source: The American Journal of Cardiology - Category: Cardiology Authors: Source Type: research
This study aimed to investigate the effects of overweight/obesity on haematoma formation following tissue expander-based breast reconstruction.
Source: Journal of Plastic, Reconstructive and Aesthetic Surgery - Category: Cosmetic Surgery Authors: Source Type: research
AbstractAim : Type 3 von Willebrand disease (VWD) is the most severe form of VWD, characterized by a near-total absence of von Willebrand factor (vWF) leading to a huge deficiency in plasmatic factor VIII (FVIII). VWD may be confused with hemophilia A, sometimes leading to misdiagnosis. The purpose of this work was to finalize the biological diagnosis of patients with FVIII activity deficiency in Abidjan, in order to guide the best type of management.Methods: We conducted a cross-sectional descriptive study from June 2018 to April 2019. Forty-nine patients, all of whom had lower FVIII levels or had been referred for b...
Source: Mediterranean Journal of Hematology and Infectious Diseases - Category: Hematology Authors: Source Type: research
ABO blood group has a profound influence on hemostasis as it is a major determinant of plasma levels of von Willebrand Factor. In vitro studies suggest that blood group O is a risk factor for increased severe bleeding while blood group non-O is a risk fact...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
More News: Bleeding | Economics | Men | Post Traumatic Stress Disorder | Psychology | von Willebrand Disease