JAG1 overexpression contributes to Notch1 signaling and the migration of HTLV-1-transformed ATL cells

HTLV-1 is a retrovirus that infects over 20 million people worldwide and is responsible for the hematopoietic malignancy adult T cell leukemia (ATL). We previously demonstrated that Notch is constitutively act...

Source: Journal of Hematology and Oncology - September 19, 2018 Category: Hematology Authors: Marcia Bellon, Ramona Moles, Hassiba Chaib-Mezrag, Joanna Pancewicz and Christophe Nicot Tags: Research Source Type: research