T cells in patients with narcolepsy target self-antigens of hypocretin neurons

T cells in patients with narcolepsy target self-antigens of hypocretin neuronsT cells in patients with narcolepsy target self-antigens of hypocretin neurons, Published online: 19 September 2018; doi:10.1038/s41586-018-0540-1The detection of hypocretin-specific autoreactive CD4+ and CD8+ T cells in patients with narcolepsy reveals the autoimmune aetiology of this disorder.

Source: Nature AOP - September 19, 2018 Category: Research Authors: Daniela Latorre Ulf Kallweit Eric Armentani Mathilde Foglierini Federico Mele Antonino Cassotta Sandra Jovic David Jarrossay Johannes Mathis Francesco Zellini Burkhard Becher Antonio Lanzavecchia Ramin Khatami Mauro Manconi Mehdi Tafti Claudio L. Bassetti Source Type: research