Renal functional diagnostics using magnetic resonance imaging.

[Renal functional diagnostics using magnetic resonance imaging]. Radiologe. 2018 Sep 17;: Authors: Kirsch H, Mentzel HJ Abstract Due to progress in the development of sequences and techniques magnetic resonance imaging (MRI) methods, such as functional MR urography (fMRU), arterial spin labeling (ASL), diffusion-weighted imaging (DWI), diffusion tension imaging (DTI) and blood oxygen level dependent MRI (BOLD-MRI) have become available for renal functional evaluation. In recent years research of these imaging techniques has demonstrated that they provide valid functional data with respect to renal perfusion, oxygenation and interstitial diffusion as well as glomerular filtration and the extent of an obstructive uropathy. Many pathophysiological renal processes, e. g. in transplanted kidneys, in the setting of chronic kidney disease and in the diagnostics of renal tumors, can therefore be fully evaluated. The fMRU, which enables a reliable assessment of renal function combined with high-resolution morphological evaluation of the kidneys and the entire urinary tract, has already become an inherent component in the clinical setting, at least in specialized pediatric radiology centers. To establish the new imaging methods in the clinical routine, further technical improvements and large-scale prospective clinical studies are necessary to validate the determined functional parameters, to generate standard protocols and to unify and facilitate data post-proc...
Source: Der Radiologe - Category: Radiology Authors: Tags: Radiologe Source Type: research

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We present and discuss the available evidence from basic science and clinical studies, and highlight perspectives for further research.
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Source: Frontiers in Physiology - Category: Physiology Source Type: research
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