Sensors, Vol. 18, Pages 3163: Indirect Microcontact Printing to Create Functional Patterns of Physisorbed Antibodies

This study presents the approach, assesses bovine serum albumin as backfilling agent for indirect µCP on different materials, reports the limitations of standard µCP on the functionality of patterned antibodies, and demonstrates the capabilities of indirect µCP to solve this issue. Bioreceptors were herein structured as diffractive gratings and used to measure biorecognition events in label-free conditions. Besides, as a preliminary approach towards sensing biomarkers, this work also reports the implementation of indirect µCP in an immunoassay to detect human immunoglobulin E.
Source: Sensors - Category: Biotechnology Authors: Tags: Article Source Type: research