New analysis methodology may revolutionize breast cancer therapy

Stroma cells are derived from connective tissue and may critically influence tumor growth. This knowledge is not new. However, a team of researchers has developed a novel methodology for investigation. Using modern mass spectrometry, tumor-promoting activities from breast fibroblasts were directly determined from needle biopsy samples.
Source: ScienceDaily Headlines - Category: Science Source Type: news

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Publication date: Available online 17 December 2018Source: Meta GeneAuthor(s): Andrea Mary Francis, R. Ramya, Nalini Ganesan, P. Kumarasamy, Solomon F.D. Paul, A.K. Munirajan, M. DivyaAbstractThe most common cancer in women is breast cancer, and it poses serious health issues in women, leading to increased mortality rates. Estrogen and its metabolites have been established as risk factors for breast cancer. Determining the role of genetic variants having functional involvement in regulating the estrogen concentration and detoxifying the toxic estrogen metabolites through estrogen hydroxylation by CYP1A1, CYP1B1, and catech...
Source: Meta Gene - Category: Genetics & Stem Cells Source Type: research
A new study assesses the bacterial origin of odors present in malignant breast wounds by identifying the volatile organic compounds produced by bacterial strains.Wounds
Source: Medscape Today Headlines - Category: Consumer Health News Tags: General Surgery Journal Article Source Type: news
Peter explains how his breast cancer treatment affected him.
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news
rlard-Davenport African American women are substantially underrepresented in breast cancer genetic research studies and clinical trials, yet they are more likely to die from breast cancer. Lack of trust in the medical community is a major barrier preventing the successful recruitment of African Americans into research studies. When considering the city of Memphis, TN, where the percentage of African Americans is significantly higher than the national average and it has a high rate of breast cancer mortality inequities among African American women, we evaluated the feasibility of utilizing a community-based participator...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Conclusions: Cooking red meat by a deep-frying method, lack of physical activity, having a higher BMI particularly during the postmenopausal period, and nonadherence to the Mediterranean diet are risk factors of breast cancer.
Source: Nigerian Journal of Clinical Practice - Category: Rural Health Authors: Source Type: research
Le Ngoc Quyen Tran Nanogel-based systems loaded with single anticancer drugs display miscellaneous effectiveness in tumor remission, gradually circumventing mutation and resistance in chemotherapy. Hence, the existence of dual-drug delivered nano-sized systems has been contemporaneous with drug development and preceded the conventional-dose chemotherapy. Among outstanding synergistic drug nanoplatforms, thermosensitive copolymer heparin-Pluronic F127 (Hep-F127) co-delivering cisplatin (CDDP) and curcumins (Cur) (Hep-F127/CDDP/Cur) has emerged as a notable candidate for temperature-responsive drug delivery. The proce...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Early stage medical equipment developer EhmetDX said late last week that it won FDA 510(k) clearance for its 3D CBCT positioning software. The Plymouth, Mich.-based company said that the newly cleared system is designed to guide the position of proton beams in patient treatments. The system is slated to be used in patient treatment at the McLaren Proton Therapy Center beginning this month, EhmetDx said. “We look forward toward patient treatment using our software for positioning now that the FDA concluded that our X-ray positioning system has met the requirements needed for 510(k).  With patient treatment immine...
Source: Mass Device - Category: Medical Devices Authors: Tags: Food & Drug Administration (FDA) Regulatory/Compliance ehmetdx Source Type: news
Oxybutynin, a drug widely used to treat urinary incontinence caused by an overactive bladder, helps treat hot flashes in breast cancer survivors and women who did not have breast cancer but who were bothered by frequent or severe menopausal symptoms, new research shows.
Source: WebMD Health - Category: Consumer Health News Source Type: news
Nearly half of all breast cancer patients do not meet the criteria for genetic testing, even though they are almost as likely to have a pathogenic variant as those who do meet the criteria.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
Condition:   Breast Cancer Intervention:   Other: Questionnaire Sponsor:   Hospices Civils de Lyon Not yet recruiting
Source: - Category: Research Source Type: clinical trials
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