Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls.

CONCLUSIONS: Given the unique character of each study design, the convergent findings for these eight psychiatric conditions suggest that heritability estimates are robust across different methods. The findings also highlight large differences in genetic and environmental influences between psychiatric disorders, providing future directions for etiological psychiatric research. PMID: 30221610 [PubMed - as supplied by publisher]
Source: Psychological Medicine - Category: Psychiatry Authors: Tags: Psychol Med Source Type: research

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The precise regulation of synaptic dopamine (DA) content by the DA transporter (DAT) ensures the phasic nature of the DA signal, which underlies the ability of DA to encode reward prediction error, thereby driving motivation, attention, and behavioral learning. Disruptions to the DA system are implicated in a number of neuropsychiatric disorders, including attention deficit hyperactivity disorder (ADHD) and, more recently, autism spectrum disorder (ASD). An ASD-associated de novo mutation in the SLC6A3 gene resulting in a threonine-to-methionine substitution at site 356 (DAT T356M) was recently identified and has been show...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Conclusion The analysis of narratives may offer an idea on the complexity of the perception of care by professionals and on the need for an interdisciplinary follow-up of women surviving an SMM or an MNM episode.Resumo Objetivo Diversos fatores podem afetar a sa úde e a qualidade de vida das mulheres que tiveram um episódio de morbidade materna grave (MMG) ou near-miss materno (NMM). O objetivo do presente estudo foi explorar as perspectivas dos profissionais sobre as repercussões da MMG ou do NMM após terem entrevistados mulheres que sobreviveram a um desses episódios. Métodos Cas...
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
Conclusion We recommend suture for hemostasis during laparoscopic cystectomy.Resumo Objetivo O objetivo desta revis ão foi comparar o impacto dos diferentes métodos hemostáticos na reserva ovariana durante a ooforoplastia laparoscópica. Fontes de Dados Os estudos foram identificados através da pesquisa de bases de dados eletrônicas (MEDLINE, Embase, Cochrane, LILACS) e listas de referência de artigos. S eleção dos estudos Selecionamos ensaios clínicos que avaliaram a influência das técnicas hemostáticas na reserva ovariana em pacientes ...
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
(Medical College of Georgia at Augusta University) When someone is depressed and having suicidal thoughts or their depression treatment just isn't working, their caregivers might want to check to see if they have obstructive sleep apnea, investigators say.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
The government has confiscated about 30,000 bottles of alcohol suspected to be poisoned with methanol
Source: Health News: - Category: Consumer Health News Source Type: news
SUMMARY BACKGROUND: Depression and anxiety disorders (DAD) are the most prevalent mental health conditions worldwide. Among the adult population served in basic care, it is estimated that depression affects about 14.3% of these individuals worldwide, and between 21.4% and 31% in Brasil. Anxiety affects up to 33.7% of the population during their lifetimes. OBJECTIVES: estimate the prevalence proportions of DAD among patients in a municipality in Northeast Brasil and study the association between DAD and cardiovascular risk factors. METHODS: a cross-sectional study with the medical records of patients from primary care cente...
Source: Revista da Associacao Medica Brasileira - Category: General Medicine Source Type: research
This study aimed to assess the prevalence of medical and nonmedical use of psychiatric medication among undergraduate students of health sciences from a public university in Brasil. Another objective was to determine the frequency of nuclear morphological abnormalities in the buccal mucosa of students using psychiatric drugs. A cross-sectional study based on a Web survey was carried out with 375 health sciences undergraduate students from schools of Pharmacy, Physical Education, Nutrition, and Medicine. Additionally, spontaneous genetic damages in exfoliated cells of the buccal mucosa of 41 individuals by counting micronuc...
Source: Revista da Associacao Medica Brasileira - Category: General Medicine Source Type: research
Health officials confiscated 30,000 bottles of alcohol and suspect the deaths were caused by methanol poisoning.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Alcoholic Beverages Costa Rica Poisoning and Poisons Deaths (Fatalities) Counterfeit Merchandise Source Type: news
In her book Mind Fixers: Psychiatry ’s Troubled Search for the Biology of Mental Illness, historian Anne Harrington challenges psychiatrists to embrace complexity. Her central message is that society has often projected a lot onto psychiatry, with our field far too eager to accept these and to fill an expertise void: at one point, w ith psychoanalytic grandiosity, later with overpromised, underperforming biological boasts and reified diagnostic labels. Echoing Foucault, Harrington invites us to avoid mistaking the name of the thing for the thing itself and to keep struggling for answers, embracing a slow science, mar...
Source: Journal of the American Academy of Child and Adolescent Psychiatry - Category: Psychiatry Authors: Tags: Book forum Source Type: research
BOSTON (CBS) — How often do you think, “I should take a mental health day?” Oregon is becoming one of the first states to allow students to do just that. Oregon’s governor signed the bill into law last month which would allow students to take mental health days just like they would sick days. The state has some of the highest suicide rates in the country and it was students who organized and lobbied for expanded mental health services. Critics believe the law wasn’t necessary, saying that students could just lie or pretend to be sick. But advocates hope that treating anxiety or depression the ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Education Health Healthwatch Seen On WBZ-TV Syndicated Local Dr. Mallika Marshall Mental Health Source Type: news
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