Plant mRNA decay: extended roles and potential determinants.

Plant mRNA decay: extended roles and potential determinants.
Curr Opin Plant Biol. 2018 Sep 14;45(Pt A):178-184
Authors: Li B, Wu H, Guo H
Abstract
The decay of mRNA in plants is tightly controlled and shapes the transcriptome. The roles of this process are to digest RNA as well as to suppress exogenous and endogenous gene silencing by preventing siRNA generation. Recent evidence suggests that mRNA decay also regulates the accumulation of the putative 3' fragment-derived long non-coding RNAs (3'lncRNAs). The generation of siRNA or 3'lncRNA from a selective subset of mRNAs raises a fundamental question of how the mRNA decay machineries select and determine their substrate transcripts for distinctive decay destiny. Evidence for potential mRNA decay determinants, such as codon bias, GC content and N6-methyladenosine (m6A) modification, is rapidly emerging. This paper aims to review the recent discoveries in plant mRNA decay.
PMID: 30223189 [PubMed - as supplied by publisher]

Source: Current Opinion in Plant Biology - September 14, 2018 Category: Biology Authors: Li B, Wu H, Guo H Tags: Curr Opin Plant Biol Source Type: research