XACT Brings in Funding and CE Mark for Robotics Navigation System

XACT Robotics has received CE mark for its robotics navigation steering system. On top of that, the Caesarea, Israel-based company has raised about $5 million in a series C round. How’s that for being efficient? The company said the funds will mainly be used for the launch and operation of seven Centers of Excellence in the US, Europe, and Israel, where the company expects that hundreds of clinical procedures will be conducted within the next 12 months with the XACT robotic navigation and steering system. The XACT robotics system is currently approved and being used for CT-guided percutaneous procedures in the abdomen. Later this year, the system's application is expected to be expanded for use in additional clinical centers and with other imaging modalities, such as Cone-Beam CT and Fluoroscopy, and for additional indications, including spinal and lung procedures. "The CE Mark approval is a key achievement for XACT and an important milestone towards entering the European market," Chen Levin, CEO of XACT Robotics, said in a release. "In parallel, the closing of our latest financial round will enable us to initiate the launch of our robotics system next year, while continuing to develop additional features for the system. Our Center of Excellence in Hadassah Medical Center is the first of seven centers that we plan to launch by the end of this year in leading medical centers in the US, Europe and Israel. The goal of these centers is to gain add...
Source: MDDI - Category: Medical Devices Authors: Tags: Business Source Type: news

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Artem Sokolov1, Stephanie Ashenden2,3, Nil Sahin4,5, Richard Lewis2, Nurdan Erdem4, Elif Ozaltan4, Andreas Bender2, Frederick P. Roth5,6,7 and Murat Cokol1,4,5,8* 1Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, United States 2Centre for Molecular Informatics, Department of Chemistry, University of Cambridge, Cambridge, United Kingdom 3Discovery Sciences, IMed Biotech Unit, AstraZeneca R&D, Cambridge, United Kingdom 4Faculty of Engineering and Natural Sciences, Sabanc─▒ University, Istanbul, Turkey 5Donnelly Centre, University of Toronto, Toronto, ON, Canada 6Department of Molecular Gene...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Conclusion Several TISC-based immunotherapeutic approaches are under development in various stages of preclinical studies. As outlined in this review article, a careful and more exhaustive genetic and metabolic understanding of TISC-associated phenotypes is critical to develop novel TISC based immunotherapies. Various components within the tumor microenvironment such as tumor cells, infiltrating immune cells, and supporting stromal cells impact the TISC metabolism. This unique metabolic profile leads to upregulation of certain enzymes and proteins such as ALDH1, CEP55, IDO COA1 etc., which can be utilized for development ...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
AbstractPrimary graft dysfunction (PGD) remains the leading cause of early mortality post-heart transplantation. Despite improvements in mechanical circulatory support and critical care measures, the rate of PGD remains significant. A recent consensus statement by the International Society of Heart and Lung Transplantation (ISHLT) has formulated a definition for PGD. Five years on, we look at current concepts and future directions of PGD in the current era of transplantation.
Source: Heart Failure Reviews - Category: Cardiology Source Type: research
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Source Type: research
Long-term survival after lung transplantation remains limited by the development of chronic lung allograft dysfunction (CLAD), which affects approximately 50% of lung recipients by 5 years post-transplant.1 Given the lack of a proven therapy once CLAD is diagnosed, risk factor mitigation is a key preventive strategy. The principal risk factor for CLAD is A-grade acute cellular rejection (ACR). A-grade ACR is diagnosed by transbronchial biopsy (TBB), exhibiting perivascular mononuclear cell infiltrates that extend into the interstitium with higher grade rejection.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: EDITORIAL Source Type: research
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Source Type: research
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Source Type: research
A Nova Scotia woman has received a double lung transplant just months after she thought the financial burden of the procedure would force her into palliative care.
Source: CBC | Health - Category: Consumer Health News Tags: News/Canada/Nova Scotia Source Type: news
Authors: Feng M, Yang X, He Y Abstract AIM: Present study was performed to explore the effects of bronchial provocation test (BPT) and bronchial dilation test (BDT) for the diagnosis of lung diseases. METHODS: BPT and BDT results were respectively detected by methacholine and albuterol in patients with different lung diseases and non-lung diseases. BPT and BDT indexes including exhaled nitric oxide (ENO), forced expiratory volume of first minute (FEV1), forced vital capacity (FVC), diffusion of carbon monoxide in the lungs (DLCO) and eosinophilia (EOS) were compared by t-test between different groups. RESUL...
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
CONCLUSION: These new recommendations, close to French practices, help clinicians to find the right time for referral of patients to transplantation centers. This is crucial for the prognosis of lung transplantation. PMID: 31006579 [PubMed - as supplied by publisher]
Source: Revue des Maladies Respiratoires - Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research
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