Cell-to-cell transmission of HSV-1 in differentiated keratinocytes promotes multinucleated giant cell formation
The herpes simplex viruses (HSVs) are neurotropic and epidermotropic viruses that cause a wide range of clinical disorders with primary and recurrent infections. A disseminated HSV-1 infection of the skin, eczema herpeticum, is commonly seen in patients with atopic dermatitis, suggesting impaired barrier function and dysregulated immune response in these patients [1,2].
Source: Journal of Dermatological Science - Category: Dermatology Authors: Yoshiko Yamamoto, Takenobu Yamamoto, Yumi Aoyama, Wataru Fujimoto Source Type: research
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