Response to erythropoietin in pediatric patients with chronic kidney disease: insights from an in vitro bioassay
ConclusionsOur findings support the presence of erythropoiesis inhibitory substances in uremic sera. EPO/EPO-R-dependent mechanisms may play a role in inhibiting erythropoiesis. The in vitro bioassay described herein may serve as an indicator of rHuEPO responsiveness which may encourage further investigation of underlying mechanisms of EPO resistance.
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
More News: Anemia | Children | Chronic Kidney Disease | Dialysis | Environmental Health | Hemodialysis | Laboratory Medicine | Pediatrics | Study | Urology & Nephrology