Two $1.5 million grants allow Wake Forest Baptist to join national stroke study

Two five-year grants worth about $1.5 million each will allow Wake Forest Baptist Medical Center to join national clinical trials in the areas of neuroscience and stroke prevention. The first grant places WFBMC among 24 other clinical sites in the Network for Excellence in Neuroscience Clinical Trials, known as NeuroNEXT. The network originated in 2011, and works to create efficiency and foster advancement in treatments for neurological diseases. The second grant adds the h ealth care network…
Source: Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news

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PMID: 31109499 [PubMed - in process]
Source: Canadian Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Can J Ophthalmol Source Type: research
This article also addresses the neuropharmacological potential of taurine analogs.Graphical abstract
Source: Redox Biology - Category: Biology Source Type: research
Conclusions: The results suggest the clinical feasibility of supplementing or substituting human transcriptions with computer-generated scores, though extension to other speech disorders requires further research.Folia Phoniatr Logop
Source: Folia Phoniatrica et Logopaedica - Category: Speech-Language Pathology Source Type: research
o-Negrete J Abstract Stroke is a leading cause of motor disability worldwide. Upper limb rehabilitation is particularly challenging since approximately 35% of patients recover significant hand function after 6 months of the stroke's onset. Therefore, new therapies, especially those based on brain-computer interfaces (BCI) and robotic assistive devices, are currently under research. Electroencephalography (EEG) acquired brain rhythms in alpha and beta bands, during motor tasks, such as motor imagery/intention (MI), could provide insight of motor-related neural plasticity occurring during a BCI intervention. Hence, ...
Source: Neural Plasticity - Category: Neurology Authors: Tags: Neural Plast Source Type: research
We examined functional connectivity (FC) of language networks in children with arterial and venous perinatal stroke and typically developing controls (TDC) in a population-based, controlled, cohort study. Resting state functional MRI was performed at 3 T (TR/TE = 2000/30 ms, 150 volumes, 3.6mm3 voxels). Seed-based analyses used bilateral inferior frontal and superior temporal gyri. A subset of stroke participants completed clinical language testing.Sixty-six children participated (median age: 12.85±3.8y, range 6–19; arterial N = 17; venous N = 15; TDC N = 34]. Children with left hemisphere ...
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Authors: Faggiano P, Fattirolli F, Frisinghelli A, Piccioli L, Dasseni N, Silverii MV, Albricci L, D'Ambrosio G, Garrì R, Esposito L, Giallauria F Abstract The present study aims at evaluating the achievement of blood pressure, lipid and blood glucose targets, healthy lifestyle changes and appropriate drug prescription/adherence in patients attending secondary prevention/CR ambulatory visit after index cardiovascular event in a time period ranging 1 to 5 year. At ambulatory visit, a predetermined set of data collection was used, including demographic data, cardiovascular risk factors and lifestyle habits, ty...
Source: Monaldi Archives for Chest Disease - Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research
This study aims to explore the best antithrombotic strategy for AF patients after PCI based on a network meta-analysis. This study was registered in PROSPERO (CRD42018093928). The PubMed, Cochrane, and EMBASE databases were searched to identify clinical trials concerning antithrombotic therapy for AF patients with PCI from inception to April 2018. Pairwise and network meta-analysis were conducted to compare clinical outcomes of different antithrombotic therapy. The primary endpoint was major bleeding. Fifteen studies including 16,382 patients were identified with follow-up ranging from 3 to 12 months. Non-vitamin K oral an...
Source: International Heart Journal - Category: Cardiology Tags: Int Heart J Source Type: research
Background: Neurogenic pulmonary edema (NPE) is characterized by acute respiratory distress triggered by acute, severe compromise of the central nervous system (CNS). This review aims at summarizing and discussing recent and previous findings about the type and frequency of CNS triggers of NPE, pathogenesis, diagnosis, treatment, and outcome of patients experiencing NPE.Key Messages: NPE is diagnosed in the presence of pink, frothy sputum, pulmonary edema, bilateral opacities on X-ray, PaO2:PiO2 #x3c;200 mm Hg, acute CNS compromise with increased intra-cranial pressure, rapid resolution within 48 –72 h, and the absen...
Source: European Neurology - Category: Neurology Source Type: research
“ For healthy people without heart problems or diabetes, up to one egg a day should be O.K., ” said one researcher.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Eggs Cholesterol Diabetes Stroke Source Type: news
Conclusion: About a quarter of patients discharged in sinus rhythm after an acute STEMI have IAB. Patients with aIAB have a poor prognosis, although this is explained mainly by the association of aIAB with age and other variables.Cardiology 2019;142:109 –115
Source: Cardiology - Category: Cardiology Source Type: research
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