Treatment of Chronic Hepatitis B Infection

To the Editor Dr Tang and colleagues summarized the current clinical evidence on the management of chronic hepatitis B virus (HBV) infection. I have some concerns about the review. First, it is not adequate to designate HBV e antigen (HBeAg) as HBV envelope antigen. HBeAg is not a structural component of HBV itself, but a derivative of HBV core antigen (HBcAg) that is secreted into the circulation during viral replication. The HBV envelope does not contain HBeAg.
Source: JAMA - Category: General Medicine Source Type: research