Increasing burden of noninfectious lung disease in persons living with HIV: a 7-year study using the French nationwide hospital administrative database

An overall reduction in the incidence of AIDS and a change in the spectrum of lung disease have been noticed in persons living with HIV (PLHIV). Our aim was to provide an epidemiological update regarding the prevalence of lung diseases in PLHIV hospitalised in France. We analysed the prevalence of lung disease in PLHIV hospitalised in France from 2007 to 2013, from the French nationwide hospital medical information database, and assessed the association between HIV and incident noninfectious disease over 4 years of follow-up. A total of 52 091 PLHIV were hospitalised in France between 2007 and 2013. Among PLHIV hospitalised with lung disease, noninfectious lung diseases increased significantly from 45.6% to 54.7% between 2007 and 2013, whereas the proportion of patients with at least one infectious lung disease decreased significantly. In 2010, 10 067 prevalent hospitalised PLHIV were compared with 8 244 682 hospitalised non-PLHIV. In 30–49-year-old patients, HIV infection was associated with chronic obstructive pulmonary disease (COPD), chronic respiratory failure, emphysema, lung fibrosis and pulmonary arterial hypertension (PAH) even after adjustment for smoking. The emergence of noninfectious lung disease, in particular COPD, emphysema, lung fibrosis, PAH and chronic respiratory disease, in PLHIV would justify mass screening in this population.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Original Articles: Rare lung diseases Source Type: research

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ConclusionNo significant difference was found in the clinical manifestations, mortality, and complication between children and adults but children tended to have lesser chance of using alternative antibiotics, methylprednisolone and inhaled NO. The chance of associated cytomegalovirus (CMV) disease was also significantly lower in children.
Source: Journal of Microbiology, Immunology and Infection - Category: Microbiology Source Type: research
Publication date: Available online 21 May 2019Source: Comptes Rendus PhysiqueAuthor(s): Guy LavalAbstractAt their very beginning, the researches on the magnetic confinement fusion had to face up plasma instabilities. Macroscopic plasma instabilities were the first ones to be identified and they were found to be very harmful for plasma confinement. During the first years after the Atoms for Peace Meeting in 1958, the main goals of experimental and theoretical researches dealt with their suppression or control. During this period, two special types of instabilities, the localized interchange modes and the tearing modes, were...
Source: Comptes Rendus Physique - Category: Physics Source Type: research
Abstract OBJECTIVE: To determine the use of home care services in those with and without visual impairment in Canada. DESIGN: Population-based cross-sectional study. PARTICIPANTS: Participants came from the baseline examination of the Canadian Longitudinal Study on Aging Comprehensive Cohort. Inclusion criteria included age between 45 and 85 years, community dwelling, and living near one of the 11 data collection sites across 7 Canadian provinces. People were excluded if they were in an institution, were living on a First Nations reserve, were full-time members of the Canadian Armed Forces, did not speak...
Source: Canadian Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Can J Ophthalmol Source Type: research
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Source: Canadian Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Can J Ophthalmol Source Type: research
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Source: Canadian Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Can J Ophthalmol Source Type: research
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Source: Molecular Phylogenetics and Evolution - Category: Molecular Biology Source Type: research
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Source: Oman Medical Journal - Category: Middle East Health Tags: Oman Med J Source Type: research
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Source: Environmental Toxicology and Pharmacology - Category: Environmental Health Source Type: research
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Source: Peerview CME/CE Video Podcast - Internal Medicine International - Category: Internal Medicine Authors: Tags: Science, Medicine Source Type: video
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Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
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