Meta-analyses using real-world data to generate clinical and epidemiological evidence: a systematic literature review of existing recommendations.

CONCLUSIONS: The inclusion of RWE in MAs may facilitate the confirmation of conclusions drawn from randomized controlled trials and thus reassure decision-makers that findings can be extrapolated to real-world populations. However, qualitative and quantitative bias may coexist in MAs of RWE. Reviewers should select the most appropriate tools that match the study designs identified in a particular systematic review. PMID: 30217138 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research