Anesthetic management of patients with systemic mastocytosis

Systemic mastocytosis is a rare disease of mast cell proliferation in multiple organs and carries a risk of anaphylactic reaction by degranulation induced by physical and psychological stimuli, alcohol, elevated temperature, and drugs known to release histamine [1, 2]. Although the prevalence is unknown, familial occurrences are unusual and equally in both sexes. Various drugs and physical and psychological stimuli can trigger degranulation of mast cells, which can cause anaphylaxis. General anesthesia is also potentially hazardous.
Source: Journal of Clinical Anesthesia - Category: Anesthesiology Authors: Tags: Correspondence Source Type: research