Dosimetric assessment of tumor control probability in intensity and volumetric modulated radiotherapy plans.

CONCLUSION: There are variations with different radiobiological models. Understanding of the correlation and limitation of a TCP model with dosimetric parameters can help develop the meaningful objective functions for plan optimization, which would lead to the implementation of outcome-based planning. More clinical data are needed to refine and consolidate the model for accuracy and robustness. Advances in knowledge: This study has tested three radiobiological models with varied disease sites. It is significant to compare different models with the same data set for better understanding of their clinical applicability. PMID: 30209959 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30209959?dopt=Abstract

Source: The British Journal of Radiology - September 13, 2018 Category: Radiology Authors: Wang H, Cooper BT, Schiff P, Sanfilippo NJ, Wu SP, Hu KS, Das IJ, Xue J Tags: Br J Radiol Source Type: research