Treatment of Ciprofloxacin-resistant Ear Infections
This study investigates ciprofloxacin-resistant infections and seeks to develop a better understanding of treatment options and outcomes.
Study Design:
Retrospective review of 141 ciprofloxacin-resistant otologic infections.
Setting:
Tertiary-care hospital.
Patients:
Patients with culture-proven ciprofloxacin-resistant infections from 2008 to 2017.
Intervention(s):
Antibiotic treatment with ciprofloxacin topical drops, ciprofloxacin plus oral antibiotics, and nonciprofloxacin therapy.
Main Outcome Measure(s):
Bacteriology for ciprofloxacin-resistant infections and treatment effectiveness of various therapies.
Results:
Methicillin-resistant Staphylococcus aureus (33%), Corynebacterium striatum (19%), and non-Methicillin-resistant Staphylococcus aureus (11%) are the most frequent causes of ciprofloxacin-resistant infections. Topical ciprofloxacin monotherapy was successful in 2.7% of infections compared with a 64.7% success rate with the addition of an oral antibiotic (p
Source: Otology and Neurotology - Category: ENT & OMF Tags: Middle Ear and Mastoid Disease Source Type: research
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