Successful Lung Re-transplant in a Patient with Cepacia Syndrome due to Burkholderia ambifaria

Chronic airway inflammation and infection drive morbidity and mortality among patients with cystic fibrosis (CF). While Haemophilus influenzae and Staphylococcus aureus predominate in children, the prevalence of Pseudomonas aeruginosa increases as patients age. Other bacteria, including species within the Burkholderia cepacia complex (Bcc), are also more prevalent among adults with CF. Species within the Bcc accelerate lung function decline and can trigger development of “cepacia syndrome,” both before and after lung transplantation.

Source: Journal of Cystic Fibrosis - September 14, 2018 Category: Respiratory Medicine Authors: Kellie J. Goodlet, Michael D. Nailor, Ashraf Omar, Jasmine L. Huang, John J. LiPuma, Rajat Walia, Sofya Tokman Tags: Case Report Source Type: research