Antibodies against human parvovirus B19 in pregnant women in Ogbomoso, Oyo State Nigeria.

This study was carried out to determine the incidence of specific IgM antibodies to HPVB19 among pregnant women attending Bowen University Teaching Hospital, Ogbomoso, Oyo State. A total of 185 participants, in the age range 18-49 years, who consented voluntarily after thorough explanation of the purpose of the study were recruited for the study. Specific IgM antibodies were detected using commercially available third-generation ELISA kits. Data on socio-demographic characteristics and potential risk factors were collected using structured questionnaires. Chi-square (χ2) test was utilized to assess the association between the socio-demographic variables and HPVB19 status (P ˂ 0.05). Logistic regression was done to determine the strength of association between the potential risk factors and HPVB19 status (P ˂ 0.05). The overall incidence of IgM antibody recorded was 2.70% (5/185). Pregnant women in the age group 36-45 (7.7%) years had the highest record. None of the socio-demographic characteristics and risk factor considered were significantly associated with acquiring HPVB19. However, a one-fold risk was observed among those who had previous history of blood transfusion (95% CI = 0.949-0.997, OR = 1.0) The findings in this study confirmed the presence of antibodies to HPVB19 among pregnant women in Ogbomoso. Public awareness, enlightenment, and screening for the virus should be encouraged to prevent fetal complications during pregnancy. PMID: 30212269 [Pu...
Source: Journal of Immunoassay and Immunochemistry - Category: Biochemistry Tags: J Immunoassay Immunochem Source Type: research