Lung volume reduction with endobronchial coils for patients with emphysema.
Lung volume reduction with endobronchial coils for patients with emphysema. J Thorac Dis. 2018 Aug;10(Suppl 23):S2797-S2805 Authors: Welling JBA, Slebos DJ Abstract The lung volume reduction coil treatment is a minimally invasive bronchoscopic treatment option for emphysema patients who suffer from severe hyperinflation. The treatment is aimed at a large group of patients where lung volume reduction surgery and bronchoscopic lung volume reduction using endobronchial valves are no option, or alternatively, can be offered as a bridge to lung transplantation. The nitinol coil exhibits a shape memory effect and is biologically inert. The lung volume reduction coil procedure is performed in two separate treatment sessions, targeting one lobe per session, with the contralateral lobe being treated 4 to 8 weeks after the first session. In one treatment session, around 10 to 14 coils, thereby treating an entire lobe, are being placed. Selecting optimally treated, symptomatic chronic obstructive pulmonary disease (COPD) patients with emphysema and severe hyperinflation, while avoiding significant airway disease such as asthma, chronic bronchitis and bronchiectasis, is key to achieve treatment success. Three randomized clinical trials investigating lung volume reduction coil treatment have been published until now, reporting the results of 452 treated patients up to 12 months after coil treatment. Lung volume reduction coil treatment results in significant improveme...
Publication date: Available online 22 October 2019Source: Life SciencesAuthor(s): Hira Butt, Azra Mehmood, Muhammad Ali, Saba Tasneem, Moazzam N. Tarar, Sheikh RiazuddinAbstractAimsThermal burns are the most common type of skin injuries. Clinically, the deteriorating thermal wounds have been successfully treated with skin cell sheets, suspensions or bioengineered skin substitutes. After thermal injury, oxidative microenvironment prevalent in the burnt tissue due to imbalance between production of free radicals and antioxidants defense aiding to destruction of cellular or tissue components. However, depleted antioxidant con...
Conclusionpaying attention to the prevalence of infection with Staphylococcus epidermidis in this study and similar studies, with correct use of antibiotics for treatment and observation of hygiene principles in pediatrics and neonatal wards can reduce mortality and morbidity caused by the disease.
Publication date: November 2019Source: The Lancet Respiratory Medicine, Volume 7, Issue 11Author(s): Pradeesh Sivapalan, Jens Ulrik Jensen
Publication date: November 2019Source: The Lancet Respiratory Medicine, Volume 7, Issue 11Author(s): Marc Miravitlles, Carl Llor
ConclusionsThis Eurasian teleradiology program demonstrates the feasibility of cross-border teleradiology for the provision of state-of-the-art reporting despite heterogeneity of referring medical centers and challenges like data transmission errors and language barriers. We also point out important factors for success like the usage of structured report templates.
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The report by Caserta et al derives from an investigation of infants born term and preterm studied prospectively from birth to 12 months corrected gestational age, using diaries, and collections of respiratory swabs to detect viruses at monthly visits and at times of illness. The methodology and statistical analyses used in this study are not for the faint of heart, but the bottom lines are not difficult. For those conducting clinical research on respiratory illnesses in infants and toddlers, the study validates that parents have the ability to accurately observe infants' illness and its severity using the Childhood Origin...
Condition: Chronic Obstructive Pulmonary Disease Interventions: Device: COPDPredict mobile App; Other: Usual care Sponsors: University of Birmingham; University Hospitals of North Midlands NHS Trust Not yet recruiting
Streptococcus pneumoniae, a gram-positive diplococcus, is the most common cause of bacterial pneumonia. The diagnosis of pneumococcal pneumonia is usually confirmed by chest x-ray and gram stain. The most appropriate antibiotics for treatment pneumococcal infection are macrolides, beta-lactams, and quinolones. Two vaccines, PPSV23 and PCV13, are highly effective in preventing infection.
Thanks in part to a six-person go-team testing fresh liver tissue from transplant patients at UCSF and Stanford, this young South San Francisco company has a "validating" deal.