Work environment risks for health care workers with cystic fibrosis
What makes the Antabio ’s molecule candidate so unique is that it’s not an antibiotic. Antibiotics typically work by killing bacteria, whereas this molecule aims to disable the bacteria, making it less able to attack and inflame the lungs.
THE MOTHER of stricken 13-year-old Ayden Cochrane last night made a desperate appeal for drugs bosses to save her son ’s life by giving him access to a wonder pill.
The 2013 update of the Infection Prevention and Control (IP&C) Guideline outlined recommendations to prevent the spread of CF respiratory pathogens. We aimed to investigate the current infection control practi...
A 51-year-old Caucasian male with cystic fibrosis (CF) (homozygous ΔF508) and mild obstructive lung disease (baseline forced expiratory volume in 1 second (FEV1) was 2.59L, 70% predicted), presented to our clinic with a history of recurrent fevers, cough with purulent sputum, and dyspnea on exertion. Comorbidities included chronic infection with Pseudomonas aerugi nosa, intermittent colonization with Exophiala dermatitidis, pancreatic insufficiency, adenomatous colon polyps (resected), osteopenia and CF-related diabetes.
Similar to patients with cystic fibrosis (CF) and non-CF bronchiectasis, patients with primary ciliary dyskinesia (PCD) are prone to recurrent or chronic lung infections with Pseudomonas aeruginosa. Chronic P. aeruginosa lung infection has a prevalence of up to 39% in patients with PCD  and is associated with structural damage, affecting lung function. Treatment of P. aeruginosa infection is challenging because P. aeruginosa adapts to the host environment through genotypic/phenotypic changes, promoting a reduced immune response .
Many bacteria produce and use extracellular signaling molecules such as acyl homoserine lactones (AHLs) to communicate and coordinate behavior in a cell-density dependent manner, via a communication system called quorum sensing (QS). This system regulates behaviors including but not limited to virulence and biofilm formation. We focused on Pseudomonas aeruginosa, a human opportunistic pathogen that is involved in acute and chronic lung infections and which disproportionately affects people with cystic fibrosis. P. aeruginosa infections are becoming increasingly challenging to treat with the spread of antibiotic resistance....
Genetic Testing and Molecular Biomarkers,Volume 24, Issue 1, Page 24-32, January 2020.
Condition: Cystic Fibrosis Intervention: Device: Vein Illumintion System device Sponsor: Hospices Civils de Lyon Not yet recruiting
Condition: Mucoviscidosis Intervention: Other: Intimate quality of life questionnaire Sponsor: Hospices Civils de Lyon Recruiting