Are fungi the secret to a sweet sounding violin? – Science Weekly podcast

From making violins sound beautiful, to beer and bread, to creating life-saving medicine, fungi have an array of very useful attributes. This week, a report demonstrates just how little we know about this kingdom of life and what we are set to gain if we tap into fungi as a resource.Hannah Devlin investigates.Join the discussion onFacebook andTwitterThe more mycologists study fungi, the more they ’re beginning to realise what an intriguing kingdom of life it is. Life-saving drugs like statins, penicillin and the immunosuppressants used in organ donation are all derived from fungi, as is the yeast used in bread and beer. Lesser known is that one researcher from Switzerland is making fungal- treated violins, and their sound is said to match that of a multimillion dollar Stradivarius.Hannah Devlin discusses why Stradivari ’s violins are so hard to re-create and why fungi might help withDr Francis Schwarze from the Swiss research institute,Empa.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Science Environment Fungi Music Source Type: news

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Conclusion: Of the 1.7 million participants, 1 in 10 had a high risk for CVD; among those at high risk, fewer than 3% were receiving statins or aspirin. An immense opportunity exists for risk mitigation in this substantial population. Primary Funding Source: Ministry of Finance and National Health Commission, China. PMID: 30776800 [PubMed - as supplied by publisher]
Source: Annals of Internal Medicine - Category: Internal Medicine Authors: Tags: Ann Intern Med Source Type: research
nández-Ahijado C PMID: 30776798 [PubMed - as supplied by publisher]
Source: Annals of Internal Medicine - Category: Internal Medicine Authors: Tags: Ann Intern Med Source Type: research
AbstractPurpose of ReviewTo provide an overview of recent pharmacological treatments for portal hypertension evaluated in early clinical trials, with particular emphasis on the pathophysiological basis of their use.Recent FindingsIn patients with compensated cirrhosis, even small decreases in portal pressure (as small as 1  mmHg) are associated with a lower probability of decompensation. In patients with decompensated cirrhosis, portal pressure “response” to non-selective beta-blocker (NSBB) therapy is associated with a lower mortality. When present, significant portal hypertension persists even after the ...
Source: Current Hepatitis Reports - Category: Infectious Diseases Source Type: research
ConclusionBMI  ≥ 25 kg/m2 increases the odds for ≥70% restenosis of VAO while ischemic heart disease represents an additional risk factor in stented patients. Further studies are required to established therapeutic strategies lowering the restenosis rates in overweight individuals after VAO therapy, especially ones undergoing stenting.
Source: Clinical Neuroradiology - Category: Neurology Source Type: research
Statin efficacy in primary CVD prevention might diminish with patient age, Published online: 19 February 2019; doi:10.1038/s41569-019-0171-8Statin therapy significantly reduces major vascular events irrespective of age, but less direct evidence is available on the benefit of statins for the primary prevention of cardiovascular disease in people aged>75 years, according to a meta-analysis by the Cholesterol Treatment Trialists' Collaboration.
Source: Nature Reviews Cardiology - Category: Cardiology Authors: Source Type: research
(Natural News) A class of drugs that doctors from Imperial College London say should be handed out like ketchup packets as “preventative medicine” to the public has once again been shown to be completely useless. A new study published in the peer-reviewed journal JAMA Internal Medicine found that statins, which are often hawked as the...
Source: - Category: Consumer Health News Source Type: news
ConclusionsOur results suggest that metformin users are more likely to initiate preventive therapies and engage in other healthy behaviours. Failure to account for these behaviours may introduce healthy user bias into studies evaluating the effects of oral antihyperglycemic therapies.RésuméObjectifsLe biais lié aux utilisateurs sains selon lequel les patients ayant recours aux soins de santé sont plus susceptibles d'entreprendre des traitements préventifs et d'adopter des comportements sains liés au mode de vie est bien connu dans les études observationnelles, particuli&egra...
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
This Monday evening our next podcast becomes available. Dr. Gustavo Heudebert and I discuss another article about risk prediction. This topic has become a recurring theme on the Annals On Call podcast. Why is risk prediction so important? In 2019 we make many decisions about prevention and testing based on risk prediction. In addition we also estimate harms and benefits. All these predictive models have advantages and flaws. In making a decision for statin use (another upcoming episode), we have to estimate the risk of cardiovascular events, how much taking a statin will decrease that risk, and the probability and type...
Source: DB's Medical Rants - Category: Internal Medicine Authors: Tags: Medical Rants Source Type: blogs
Source: Clinical Trials And Noteworthy Treatments For Brain Tumors - Category: Cancer & Oncology Source Type: clinical trials
The cost of cardiac care, statin adherence and mortality, syncope, ultra-processed food, and heart failure survival are discussed in this week's on Medscape
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Cardiology Commentary Source Type: news
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