No Short-Term Cancer Risk From Recalled Heart Med Valsartan: Study

THURSDAY, Sept. 13, 2018 -- People who took recalled blood pressure drugs containing a carcinogen do not appear to have a markedly increased short-term risk of cancer, a new study reports. Doctors are reluctant to say they're fully in the clear,...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news

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Publication date: Available online 16 November 2018Source: Seminars in Cancer BiologyAuthor(s): Besa Xhabija, Benjamin L. KidderAbstractEpigenetic regulation of chromatin plays a critical role in controlling stem cell function and tumorigenesis. The histone lysine demethylase, KDM5B, which catalyzes the demethylation of histone 3 lysine 4 (H3K4), is important for embryonic stem (ES) cell differentiation, and is a critical regulator of the H3K4-methylome during early mouse embryonic pre-implantation stage development. KDM5B is also overexpressed, amplified, or mutated in many cancer types. In cancer cells, KDM5B regulates e...
Source: Seminars in Cancer Biology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 16 November 2018Source: Cancer GeneticsAuthor(s): Jennelle C. Hodge, David Bosler, Lauren Rubinstein, Navid Sadri, Shashirekha ShettyAbstractThe inv(3)(q21q26.2) altering a single chromosome 3 homolog is an established myeloid malignancy-associated entity. Comparatively, double inv(3) cases involving both homologs are exceedingly rare with 13 reports across AML, CML and MDS. This scarcity was confirmed by finding only 2 new cases out of 34,898 bone marrows collected during a 55 year period at a large medical center (0.0005%). The double inv(3) was detected by karyotype and confirmed by FI...
Source: Cancer Genetics - Category: Cancer & Oncology Source Type: research
New research published inNeuro-Oncology examines the controversial link between intracranial volume and high-grade glioma.
Source: CancerNetwork - Category: Cancer & Oncology Authors: Source Type: news
Publication date: Available online 15 November 2018Source: Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)Author(s): Funda Üstün, Burcu Tokuc, Ebru Tastekin, Gülay Durmuş AltunAbstractAimIn lung cancer, axillary lymph node metastases (ALM) are rare, and according to the 8th grading system, it is classified as M1b disease. The aim of this study is to evaluate (i) the presence of ALM, and (ii) the effect of the primary tumors characteristics on the development of ALM.MethodsWe performed a descriptive cross-sectional study, with retrospective revision, to identify ALM.ResultsTh...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - Category: Nuclear Medicine Source Type: research
Authors: Gong W, Qi X Abstract Frailty is characterized by a state of vulnerability to poor resolution of homoeostasis after a stressor event and is a consequence of age-related decline in many physiological systems during a lifetime. To access the association between frailty and delayed recovery of gastrointestinal function in patients undergoing elective colorectal cancer resections, 241 patients who had undergone elective colorectal cancer resections from July 2015 to August 2017 were investigated. The association of frailty with delayed recovery of gastrointestinal function, length of stay (LOS), and whether or...
Source: Journal of Investigative Surgery - Category: Surgery Tags: J Invest Surg Source Type: research
CONCLUSIONS: Endobronchial targeting of peripheral airway targets is feasible using existing open-source technology. Notwithstanding the shortcomings of current commercial platforms, technological improvements in EM tracking and registration accuracy fostered by open-source technology may provide the impetus for widespread clinical uptake of electromagnetic navigation in bronchoscopy. PMID: 30428748 [PubMed - as supplied by publisher]
Source: Minimally Invasive Therapy and Allied Technologies - Category: Surgery Tags: Minim Invasive Ther Allied Technol Source Type: research
Linda Woolley, 73, was diagnosed with 'likely' kidney cancer at the University of Colorado Hospital in March. She had both organs removed before doctors realized she was cancer-free.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Authors: Lerner AD, Feller-Kopman D PMID: 30433839 [PubMed - as supplied by publisher]
Source: Expert Review of Respiratory Medicine - Category: Respiratory Medicine Tags: Expert Rev Respir Med Source Type: research
CONCLUSION: At 5 years after radiotherapy, median plasma BNP levels remained within the normal range, but the delta-BNP levels are directly related to the heart and ventricular dose received. PMID: 30431375 [PubMed - as supplied by publisher]
Source: International Journal of Radiation Biology - Category: Radiology Tags: Int J Radiat Biol Source Type: research
ERK5‑regulated RERG expression promotes cancer progression in prostatic carcinoma. Oncol Rep. 2018 Nov 05;: Authors: Xiong Y, Huang H, Chen S, Dai H, Zhang L Abstract Big mitogen‑activated protein kinase 1 [also named extracellular signal‑regulated kinase (ERK) 5] is activated by mitogens and oncogenic signals and is strongly implicated in tumorigenesis. Our previous investigation indicated that ERK5 can induce prostatic carcinoma cell proliferation by promoting entry into the S phase of the cell cycle. In the present study, microarray and western blot analysis revealed that ERK5 can inhibit...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
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