microRNA-935 is reduced in non-small-cell lung cancer tissue, is linked poor outcome, and acts on signal transduction mediator E2F7 and the AKT pathway.
CONCLUSION: Altered miR-935 in lung cancer biopsy tissue may be a diagnostic tool and could direct treatment. Involvement in carcinogenesis is implied by its suppression of the development of NSCLC via targeting E2F7 and inhibiting AKT pathway.
PMID: 30203720 [PubMed - as supplied by publisher]
Source: British Journal of Biomedical Science - Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research
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