Impact of sperm DNA fragmentation reduction using MACS: comparative clinical outcomes on a shared oocyte donation program

Several studies evidenced that the use of MACS (Magnetic-Activated Cell Sorting - Annexin V columns) for semen samples with high levels of DNA damage could be useful to reduce it (1). However, other studies demonstrated that there was no beneficts of using MACS. A few years ago, we published a retrospective study who showed that using MACS could improve the ongoing pregnancy rates (2) in a oocyte donation program. Thus, the present prospective controlled study aimed to evaluate the clinical outcomes using MACS in patients with sperm DNA fragmentation in a shared oocyte donation cycles.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Poster session Source Type: research