Molecular genetic analysis of weak ABO subgroups in the Chinese population reveals ten novel ABO subgroup alleles.

CONCLUSION: Ten novel weak ABO subgroup alleles were identified in the Chinese population. GTA mutant p.L339P may lead to a weak A phenotype by changing the local conformation of GTA and reducing its stability.
PMID: 30201086 [PubMed - as supplied by publisher]

Source: Blood Transfusion - September 3, 2018 Category: Hematology Authors: Huang H, Jin S, Liu X, Wang Z, Lu Q, Fan L, Shen W, Lei H, Qian C, Wang X, Xiang D, Cai X Tags: Blood Transfus Source Type: research