Sensory and descending motor circuitry during development and injury.

Sensory and descending motor circuitry during development and injury. Curr Opin Neurobiol. 2018 Sep 08;53:156-161 Authors: Plant GW, Weinrich JA, Kaltschmidt JA Abstract Proprioceptive sensory input and descending supraspinal projections are two major inputs that feed into and influence spinal circuitry and locomotor behaviors. Here we review their influence on each other during development and after spinal cord injury. We highlight developmental mechanisms of circuit formation as they relate to the sensory-motor circuit and its reciprocal interactions with local spinal interneurons, as well as competitive interactions between proprioceptive and descending supraspinal inputs in the setting of spinal cord injury. PMID: 30205323 [PubMed - as supplied by publisher]
Source: Current Opinion in Neurobiology - Category: Neurology Authors: Tags: Curr Opin Neurobiol Source Type: research