Renal function after abdominal aortic aneurysm repair in patients with baseline chronic renal insufficiency: open vs endovascular repair.

Renal function after abdominal aortic aneurysm repair in patients with baseline chronic renal insufficiency: open vs endovascular repair. Int Angiol. 2018 Sep 10;: Authors: Marques De Marino P, Martinez Lopez I, Cernuda Artero I, Cabrero Fernandez M, Pla Sanchez F, Ucles Cabeza O, Serrano Hernando FJ Abstract BACKGROUND: The aim of this study is to analyse renal function impairment (RFI) after abdominalaortic aneurysm (AAA) repair in patients with preoperative chronic kidney disease (CKD). METHODS: Retrospective cohort study of patients with CKD undergoing elective AAA repair between 2008-2015, dividing the sample into two groups: open repair (OR) and endovascular repair (EVAR). The primary outcome was RFI defined by the RIFLE scale, studying Risk (1.5-fold increase in Cr or GFR decline>25% compared to baseline) and kidney Injury (doubling of Cr or GFR decline>50%). RESULTS: N=75 patients (OR=29, EVAR=46). Baseline characteristics for OR and EVAR were similar except for age (70.4 vs 77.2 years;p
Source: International Angiology - Category: Cardiology Tags: Int Angiol Source Type: research

Related Links:

s N Abstract AIM: To compare early outcome after complex endovascular aortic repair in octogenarians (age ≥ 80 years) versus non-octogenarians (age 
Source: PubMed: Eur J Vasc Endovasc ... - Category: Surgery Authors: Tags: Eur J Vasc Endovasc Surg Source Type: research
Despite its strong link to cardiovascular outcomes, the association of chronic kidney disease (CKD) with abdominal aortic aneurysm (AAA) has not been explicitly and comprehensively investigated.
Source: Atherosclerosis - Category: Cardiology Authors: Source Type: research
Abstract Leptin, an adipokine that is implicated in the control of food intake via appetite suppression, may also stimulate oxidative stress, inflammation, thrombosis, arterial stiffness, angiogenesis and atherogenesis. These leptin-induced effects may predispose to the development of cardiovascular diseases. In the present review we discuss the evidence linking leptin levels with the presence, severity and/or prognosis of both coronary artery disease and non-cardiac vascular diseases such as stroke, carotid artery disease, peripheral artery disease (PAD) and abdominal aortic aneurysms (AAA) as well as with chroni...
Source: Acta Pharmacologica Sinica - Category: Drugs & Pharmacology Authors: Tags: Acta Pharmacol Sin Source Type: research
In conclusion, senescence of vascular cells promotes the development of age-related disorders, including heart failure, diabetes, and atherosclerotic diseases, while suppression of vascular cell senescence ameliorates phenotypic features of aging in various models. Recent findings have indicated that specific depletion of senescent cells reverses age-related changes. Although the biological networks contributing to maintenance of homeostasis are extremely complex, it seems reasonable to explore senolytic agents that can act on specific cellular components or tissues. Several clinical trials of senolytic agents are currentl...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In conclusion, senescence of vascular cells promotes the development of age-related disorders, including heart failure, diabetes, and atherosclerotic diseases, while suppression of vascular cell senescence ameliorates phenotypic features of aging in various models. Recent findings have indicated that specific depletion of senescent cells reverses age-related changes. Although the biological networks contributing to maintenance of homeostasis are extremely complex, it seems reasonable to explore senolytic agents that can act on specific cellular components or tissues. Several clinical trials of senolytic agents are currentl...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
AbstractPurposeAcute kidney injury (AKI) is a severe complication after infrarenal abdominal aortic aneurysm (iAAA) repair. Little data are available whether endovascular aneurysm (EVAR) or open aortic repair (OAR) differs with respect to AKI frequency and severity, consecutive development of chronic kidney disease (CKD) and potentially preventable and modifiable risk factors of AKI.Patients and methodsWe assessed AKI rates, AKI stages and CKD applying current, complete definitions from the kidney disease improving global outcomes initiative in propensity-score-matched cohorts of all patients with elective and urgent iAAA ...
Source: International Urology and Nephrology - Category: Urology & Nephrology Source Type: research
AbstractTo assess feasibility, efficacy and safety of carbon dioxide (CO2) digital subtraction angiography (DSA) to guide endovascular aneurysm repair (EVAR) in a cohort of patients with chronic kidney disease (CKD). After Ethical Committee approval, the records of 13 patients (all male, mean age 74.6  ± 8.0 years) with CKD, who underwent EVAR to exclude an abdominal aortic aneurysm (AAA) under CO2 angiography guidance, were reviewed. The AAA to be excluded had a mean diameter of 52.0  ± 8.0 mm. CO2 angiography was performed by automatic (n  = 7) or hand (n&thins...
Source: The International Journal of Cardiovascular Imaging - Category: Radiology Source Type: research
In this issue Dr van Eps and colleagues report on prognostic factors of acute kidney injury (AKI) and renal function decline leading to chronic kidney disease (CKD) following elective endovascular repair (EVAR) in a cohort of 212 consecutive patients with abdominal aortic aneurysm (AAA).1 Administration of an iodinated contrast agent to perform angiography during EVAR and computed tomographic angiography during follow-up to supervise the procedure and detect complications of EVAR are considered to be the main culprits in the development of AKI and subsequently CKD, observed in 15% and 23.5% of patients, respectively, in the authors' study.
Source: European Journal of Vascular and Endovascular Surgery - Category: Surgery Authors: Tags: Invited Commentary Source Type: research
Endovascular aneurysm repair (EVAR) may be associated with renal injury and more insight is needed into potential risk factors. The aim was to identify clinical, anatomical, and peri-procedural parameters as potential risk factors for the occurrence of acute kidney injury (AKI) and to evaluate chronic kidney disease (CKD) after EVAR.
Source: European Journal of Vascular and Endovascular Surgery - Category: Surgery Authors: Source Type: research
Permanent renal function decline, development and deterioration of chronic kidney disease (CKD) are associated with serious complications. How frequent is renal function decline after infrarenal abdominal aortic aneurysm (iAAA) repair according to current definitions and what are its risk factors, especially potentially modifiable ones?
Source: Annals of Vascular Surgery - Category: Surgery Authors: Source Type: research
More News: Abdominal Aneurysm Repair | Abdominal Aortic Aneurysm | Aortic Aneurysm | Cardiology | Chronic Kidney Disease | Endovascular Repair (EVAR) | Gastroschisis Repair | Study | Urology & Nephrology