Heterogeneity of cannabinoid ligand-induced modulations in intracellular Ca2+ signals of mouse pancreatic acinar cells in vitro.

In conclusion, CB2R agonists play critical roles in modulating Ca2+ signals in mouse pancreatic acinar cells, while other cannabinoid ligands modulate Ca2+ oscillations in a heterogeneous manner through a CB receptor or non-CB-receptor mechanism.
PMID: 30202013 [PubMed - as supplied by publisher]

Source: Acta Pharmacologica Sinica - September 10, 2018 Category: Drugs & Pharmacology Authors: Xia KK, Shen JX, Huang ZB, Song HM, Gao M, Chen DJ, Zhang SJ, Wu J Tags: Acta Pharmacol Sin Source Type: research