Oxycontin's Maker Now Selling Drug to Curb Opioid Addiction

Title: Oxycontin's Maker Now Selling Drug to Curb Opioid AddictionCategory: Health NewsCreated: 9/10/2018 12:00:00 AMLast Editorial Review: 9/10/2018 12:00:00 AM
Source: MedicineNet Chronic Pain General - Category: Anesthesiology Source Type: news

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Having trouble viewing this email? View it as a Web page. NIDCR's Summer 2020 E-Newsletter In this issue: NIDCR News Funding Opportunities NIH/HHS News Funding Notices Science Advances Subscribe to NICDR News Grantee News   NIDCR News NIDCR Announces Availability of COVID-19 Research Funding On May 5, NIDCR issued two Notices of Special Interest highlighting the urgent need for research on coronavirus disease 2019. This research may be conducted either via the National Dental PBRN infrastruc...
Source: NIDCR Science News - Category: Dentistry Source Type: news
Scientists identified a group of neurons in mice that blunt pain within the brain. Such neurons could be promising targets for new non-addictive therapies for chronic pain.
Source: NIH Research Matters - Category: Research Source Type: news
Over the past decade, increased awareness by the medical profession of the devastating consequences of opioid addiction has resulted in substantial efforts to limit the number of opioid prescriptions for both perioperative pain management and chronic pain. While these efforts have had some success, opioid misuse remains a crisis, which we in the orthopaedic community have a particular opportunity to address. It is the belief of the undersigned that progress depends on improved research methods and reporting to further the understanding of pain experience and response to management, with the end goal of identifying more eff...
Source: Arthroscopy - Journal of Arthroscopic and Related Surgery - Category: Surgery Tags: Editorial Source Type: research
This study is a meta-analysis — a study which includes many studies that are deemed similar enough to lump together, in order to increase the numerical power of the study and, ideally, the strength of the conclusions. The authors included studies that go all the way back to the mid-1990s — a time when cannabis was illegal in the US, different in potency, and when there was no choice or control over strains or cannabinoid compositions, as there is now. One of the studies in the meta-analysis included “cannabis dependent inpatients” in a German psychiatric hospital in which 118 patients were being det...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Addiction Marijuana Mental Health Source Type: blogs
We describe the historical use of opioids and the scope of the current opioid crisis, review the differences between dependence and addiction, and the private and public sectors response to pain management and highlight the issue of adolescent vulnerability. We conclude with a proposal for future directions that address both public and patient health needs.
Source: Current Opinion in Anaesthesiology - Category: Anesthesiology Tags: PEDIATRIC ANESTHESIA: Edited by Jorge A. Gálvez Source Type: research
This study aimed to: (1) examine changes in pain, psychosocial functioning, and health care utilization among children and adolescents with sickle cell disease (SCD) over a 2-year period and (2) identify baseline biopsychosocial variables associated with the development and maintenance of chronic SCD pain at follow-up. Materials and Methods: Forty-two youth (8 to 18 y old) with SCD completed a battery of self-report measures at baseline and 2-year follow-up. Analgesic, Anesthetic, and Addiction Clinical Trial Translational Innovations Opportunities and Networks and American Pain Society Pain Taxonomy (AAPT) diagn...
Source: The Clinical Journal of Pain - Category: Anesthesiology Tags: Original Articles Source Type: research
Purpose of review Opioids are potent drugs for the treatment of severe pain, but they are burdened by detrimental side-effects, such as respiratory depression, addiction, sedation and constipation. Their clinical application is undisputed in acute (e.g. perioperative) and cancer pain, but their use in chronic nonmalignant pain has met increasing scrutiny and has contributed to the opioid crisis. Thus, novel analgesics with reduced side-effects are badly needed. Recent findings Current research topics include enkephalinase inhibitors, allosteric and multivalent ligands, biased opioid receptor signaling and selective ac...
Source: Current Opinion in Supportive and Palliative Care - Category: Palliative Care Tags: PAIN: NON-MALIGNANT DISEASES: Edited by Anthony H. Dickenson and Kirsty Bannister Source Type: research
Conclusions: Kratom use may serve as a self-treatment strategy for a diverse population of patients with pre-existing health diagnoses. Healthcare providers need to be engaging with patients to address safety concerns and potential limitations of its use in clinical practice for specific health conditions.
Source: Journal of Addiction Medicine - Category: Addiction Tags: Original Research Source Type: research
Authors: Moryl N, Filkins A, Griffo Y, Malhotra V, Jain RH, Frierson E, Inturrisi C Abstract Cancer pain is often treated with opioids, a therapeutic regimen that can become a challenge in patients with an opioid use disorder (OUD). While use of the buprenorphine-naloxone combination is an effective medication-assisted treatment (MAT) for OUD, its use in pain patients with OUD has been controversial due to concerns that co-administration of buprenorphine can reduce or block analge-sia and precipitate opioid withdrawal in those patients requiring full opioid agonists. Data on its use in cancer pain patients are lack...
Source: Journal of Opioid Management - Category: Addiction Tags: J Opioid Manag Source Type: research
Considerable research has been conducted identifying risk factors associated with substance abuse disorders (SUD) in women. These factors include psychological and emotional distress, domestic violence, sexual abuse, weight control, fighting exhaustion, and chronic pain (NIDA: https://www.drugabuse.gov/publications/drugfacts/substance-use-in-women). Another risk factor, and common experience among substance abusing women, is the death of a family member and unresolved grief (Furr, Johnson,&Goodall, 2015; Horton, Luna,&Malloy, 2018; McComish et al., 1999; Raskin, 1992).
Source: Archives of Psychiatric Nursing - Category: Nursing Authors: Source Type: research
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