Post-malaria neurological syndrome: Imported case series and literature review to unscramble the auto-immune hypothesis

Post-malaria neurological syndrome (PMNS) is a complication that occurs after recovery from a severe Plasmodium falciparum attack. Over the past two decades, the description of several imported cases has confirmed that this syndrome is a clearly distinct entity, different from other post malarial neurological disorders. However, the underlying mechanisms are not yet elucidated. Herein, we present five imported PMNS cases managed in Marseille, France. The detection of neuronal surface antibodies to an encephalitic syndrome of unknown origin allowed us to reveal positivity of anti Voltage-Gated-Potassium Chanel antibodies (anti VGKC) in one of them.
Source: Travel Medicine and Infectious Disease - Category: Infectious Diseases Authors: Tags: Review Source Type: research