Combined Celiac Ganglia and Plexus Neurolysis Shortens Survival, Without Benefit, vs Plexus Neurolysis Alone

Pancreatic cancer produces debilitating pain that opioids often ineffectively manage. The suboptimal efficacy of celiac plexus neurolysis (CPN) might result from brief contact of the injectate with celiac ganglia. We compared the effects of endoscopic ultrasound-guided celiac ganglia neurolysis (CGN) vs the effects of CPN on pain, quality of life (QOL), and survival.

Source: Clinical Gastroenterology and Hepatology - September 11, 2018 Category: Gastroenterology Authors: Michael J. Levy, Ferga C. Gleeson, Mark D. Topazian, Larissa L. Fujii-Lau, Felicity T. Enders, Joseph J. Larson, Kristin Mara, Barham K. Abu Dayyeh, Steven R. Alberts, Christopher L. Hallemeier, Prasad G. Iyer, Michael L. Kendrick, William D. Mauck, Randa Source Type: research