Timing of DWI-MRI predicts breast cancer response

Diffusion-weighted MR images acquired 12 weeks after the start of neoadjuvant...Read more on AuntMinnie.comRelated Reading: Breast cancer follow-up imaging varies widely Breast MRI underutilized in high-risk women Multiparametric MRI shines for suspected breast cancer Is screening breast MRI being used in the wrong women? Breast MRI technique helps cancer detection without contrast
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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Publication date: Available online 10 January 2019Source: Reproductive BioMedicine OnlineAuthor(s): Matteo Lambertini, Massimo Di Maio, Francesca Poggio, Olivia Pagani, Giuseppe Curigliano, Lucia Del Mastro, Shani Paluch-Shimon, Sibylle Loibl, Ann H. Partridge, Jr. Hatem A. Azim, Fedro A. Peccatori, Isabelle DemeestereABSTRACTResearch questionWe explored the knowledge, attitudes and practice of physicians towards fertility and pregnancy-related issues in young BRCA-mutated breast cancer (BC) patients.DesignPhysicians attending two international BC conferences were asked to complete a 26-item questionnaire exploring fertili...
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
Condition:   HER-2 Negative Breast Cancer Intervention:   Drug: Chemotherapy Sponsor:   Fudan University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionFurther investigation of PD-L1 expression in breast cancer and its effect on prognosis is required. There is little consensus on the methods used to evaluate PD-L1 expression immunohistochemically, and this may contribute to the diverging results found in this study.
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research
A 59-year-old woman with a history of right-sided breast cancer presents with new onset of a right lower neck mass and numbness/paresthesia over her anterior/medial deltoid.1 Three years earlier, she received a diagnosis of stage IIIA disease (cT3N1), ER/PR+ and Her-2 nonreactive. She received neoadjuvant chemotherapy followed by modified radical mastectomy and adjuvant chemotherapy. However, she did not receive postmastectomy radiation or proper hormone therapy because of their cost.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Gray Zone Source Type: research
The Opti-HER HEART trial aimed to optimize activity while minimizing cardiac risk by combining trastuzumab, pertuzumab, and paclitaxel with non-pegylated liposomal doxorubicin in the treatment of HER2-positive...
Source: BMC Medicine - Category: Internal Medicine Authors: Tags: Research article Source Type: research
American Journal of Roentgenology, Ahead of Print.
Source: American Journal of Roentgenology - Category: Radiology Authors: Source Type: research
Abstract PURPOSE: To investigate the association of insulin like growth factor 1 receptor (IGF-1R) and estrogen receptor (ER) with pathological complete response (pCR) secondary to neoadjuvant chemotherapy in human epidermal growth factor receptor-2 (HER2)-negative breast cancer. MATERIALS AND METHODS: The immunohistochemical expressions of IGF-1R and ER were detected in puncture specimens from 273 patients who received neoadjuvant chemotherapy. Association of IGF-1R and ER expression with pCR to neoadjuvant chemotherapy was evaluated. RESULTS: In 273 cases of breast cancer, the high expression rate of I...
Source: Breast Cancer - Category: Cancer & Oncology Authors: Tags: Breast Cancer Source Type: research
Authors: Altundag K Abstract PMID: 30610827 [PubMed - in process]
Source: Journal of B.U.ON. - Category: Cancer & Oncology Tags: J BUON Source Type: research
Authors: Choi HJ, Kim JM, Ryu JM, Kim I, Nam SJ, Yu J, Lee SK, Lee JE, Kim SW Abstract Purpose: The recent trend in breast cancer treatment is to minimize axillary dissection. However, no pattern of axillary metastasis has been precisely established. The purpose of this study was to evaluate the metastatic lymphatic pattern using near-infrared fluorescence imaging with indocyanine green (ICG) in breast cancer with cytologically proven axillary metastasis. Methods: This was a prospective single-center study. We evaluated 147 patients with breast cancer involving cytologically proven axillary metastasis, and comp...
Source: Journal of Breast Cancer - Category: Cancer & Oncology Tags: J Breast Cancer Source Type: research
Conclusion: Patients with visualization of IMSLN should perform IM-SLNB after NAC, especially for patients with cN+ disease, in order to complete lymph nodal staging. IM-SLNB could further improve the definition of nodal pCR and guide the internal mammary node irradiation. PMID: 30607166 [PubMed]
Source: Journal of Breast Cancer - Category: Cancer & Oncology Tags: J Breast Cancer Source Type: research
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