Can Tetris inspire AI for MRI breast cancer detection?

Borrowing concepts used in the classic computer game Tetris, Australian researchers...Read more on AuntMinnie.comRelated Reading: Live from C-MIMI: Dr. Bradley Erickson on AI and radiology Live from C-MIMI: Dr. Eliot Siegel on AI and radiology JAMA: 7 forces will drive adoption of AI in healthcare Tetris boosts brain matter on fMRI exams
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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ConclusionsThe evidence for equine ‐assisted interventions for adults and children across a range of conditions and presentations is equivocal. The current evidence base is marred by multiple methodological weaknesses and thus, therapeutic interventions that include a horse cannot be asserted as best practice at this time. Rigorous research is indicated to determine the utility of equine‐assisted interventions.
Source: Australian Journal of Psychology - Category: Psychiatry & Psychology Authors: Tags: SPECIAL ISSUE Source Type: research
Source: OncoTargets and Therapy - Category: Cancer & Oncology Tags: OncoTargets and Therapy Source Type: research
Abstract Over the last decade there has been growing evidence that Brain Expressed X-Linked 2 (BEX2) has a significant role in the process of carcinogenesis. Collectively, available studies suggest a pro-oncogenic function for this gene in multiple malignancies, including breast, colorectal and hepatocellular cancers in addition to brain tumors. The identification of BEX2 in breast cancer resulted from gene expression microarray studies. Subsequent studies showed that BEX2 promotes breast cancer cell growth and survival by modulating the mitochondrial apoptotic pathway and G1 cell cycle. In this process, BEX2 has ...
Source: Experimental Cell Research - Category: Cytology Authors: Tags: Exp Cell Res Source Type: research
By analyzing tumor characteristics such as structure, shape, and size, an artificial...Read more on AuntMinnie.comRelated Reading: AI may predict lymph node metastasis in gastric cancer AI can predict breast cancer molecular subtypes on MRI Russian AI detects lung cancer on CT in 20 seconds AI can differentiate glioblastoma, brain metastasis AI uses features outside nodules to predict malignancy
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Opinion statementIn the past, the standard of care for treatment of BM was whole brain radiation therapy (WBRT), stereotactic radiosurgery (SRS), and surgery. There has been a greater role for medical therapies in the last two decades due to the discovery of driver mutations and corresponding targeted therapies. These innovations have dramatically altered the approach to treating these patients. Some of the important mutations include epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) mutations in small cell lung cancer, human epidermal growth factor receptor (HER2) mutation in breast cancer, and ...
Source: Current Treatment Options in Oncology - Category: Cancer & Oncology Source Type: research
Publication date: February 2019Source: Brain, Behavior, and Immunity, Volume 76, SupplementAuthor(s): C. Taub, H. Fisher, E. Nahin, B. Blomberg, M. Lippman, B. Hudson, A. Diaz, S. Lechner, T. Kwak, G. Hwang, C. Carver, M. AntoniInflammation and social adversity have been linked to poorer long-term outcomes in breast cancer (BCa) patients, whereas greater social and family well-being (sfwb) relates to less inflammation and longer disease-free interval in BCa. S100A8A9 is a RAGE-related ligand that can up-regulate inflammatory and pro-metastatic processes and has been associated with increased risk of BCa metastasis. Here we...
Source: Brain, Behavior, and Immunity - Category: Neurology Source Type: research
Conclusion.In this cohort of patients with GI cancer with brain metastases, HER2+ status was more common intracranially compared with prior sites of disease. These findings suggest that testing HER2 in patients with GI cancer with brain metastases may lead to additional therapeutic options, regardless of HER2 status in previously examined tissue.Implications for Practice.HER2 amplification is a well‐known driver of oncogenesis in breast cancer, with associated increased risk of brain metastases and response to HER2‐directed therapy. In nongastric gastrointestinal (GI) cancers, HER2 amplification is not common and conse...
Source: The Oncologist - Category: Cancer & Oncology Authors: Tags: Precision Medicine, Cancer Diagnostics and Molecular Pathology, Gastrointestinal Cancer Source Type: research
The combination of artificial intelligence (AI) and radiomics features on CT...Read more on AuntMinnie.comRelated Reading: AI can predict breast cancer molecular subtypes on MRI Russian AI detects lung cancer on CT in 20 seconds AI can differentiate glioblastoma, brain metastasis AI uses features outside nodules to predict malignancy Surgery plus RT works best for metastatic gastric cancer
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Working with radiomics data on multiparametric MRI (mpMRI) scans, an artificial...Read more on AuntMinnie.comRelated Reading: Advanced imaging offers insight into targeted therapies AI can predict breast cancer molecular subtypes on MRI AI can differentiate glioblastoma, brain metastasis CT radiomics improves management of bile duct cancer Faster MRI protocol avoids unneeded prostate biopsies
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
The objective of this study was to investigate the impact of lapatinib combined with stereotactic radiosurgery (SRS) on local control of brain metastases.METHODSPatients with HER2+ breast cancer brain metastases who underwent SRS from 1997-2015 were included. The primary outcome was the cumulative incidence of local failure following SRS. Secondary outcomes included the cumulative incidence of radiation necrosis and overall survival.RESULTSOne hundred twenty-six patients with HER2+ breast cancer who underwent SRS to 479 brain metastases (median 5 lesions per patient) were included. Among these, 75 patients had luminal B su...
Source: Journal of Neurosurgery - Category: Neurosurgery Authors: Tags: J Neurosurg Source Type: research
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