Effect of hemodialysis on corrected QT interval and QTc dispersion

PM Sohal, A Goel, D Gupta, N Aslam, J Sandhu, JS Sandhu, EE John, D SharmaIndian Journal of Nephrology 2018 28(5):335-338 Hemodialysis patients are at higher risk of cardiovascular disease due to traditional and dialysis-related risk factors. Our aim was to study the effects of hemodialysis on the corrected QT interval (QTc) and QTc dispersion in chronic kidney disease (CKD) without clinically manifest heart disease. Two hundred cases of CKD on chronic intermittent hemodialysis of >3 months' duration were included in the study. Twelve-lead electrocardiography and samples for serum creatinine, potassium, calcium, and magnesium were taken before and after dialysis. The mean age of patients was 52.4 ± 17 years with male-to-female ratio of 3:1. QTc interval and QTc dispersion were prolonged in 47% and 59% before and 50% and 89% of patients after hemodialysis, respectively. The mean values of QTc were 433.4 ± 36.9 ms before and 451.4 ± 39.6 ms after hemodialysis (p = 0.001) and the mean values of QTc dispersion were 60.5 ± 19.3 ms before and 81.5 ± 24.4 ms after hemodialysis (p = 0.001). Similar pattern was observed in all etiological groups of CKD, except for QTc dispersion in malignancy-related CKD (p = 0.216). After hemodialysis, there was a significant fall in the mean values of serum potassium (p = 0.001), rise in serum calcium (p = 0.001), and no change in magnesium (p = 0.424). Patients with post hemo...
Source: Indian Journal of Nephrology - Category: Urology & Nephrology Authors: Source Type: research

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ConclusionsDiabetes carries a significant health burden, and results vary across states. Efforts to prevent or delay diabetes or to improve diabetes management could reduce the health burden because of diabetes.
Source: American Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
THURSDAY, Dec. 6, 2018 -- Although fewer Americans are dying from heart disease and cancer, deaths from chronic kidney disease are on the rise, especially among young adults, a new study finds. " Unfortunately, chronic kidney disease is known as a...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Publication date: Available online 24 November 2018Source: Canadian Journal of CardiologyAuthor(s): Mark Hensey, Dale J. Murdoch, Janarthanan Sathananthan, David A. Wood, John G. WebbAbstractThe coexistence of chronic kidney disease (CKD) and severe aortic stenosis (AS) is common and the prevalence of both is rising. The two conditions are inherently linked in that significant CKD may accelerate the development of AS and severe AS may result in deteriorating kidney function. The volume of, and indications for transcatheter aortic valve implantation (TAVI) procedures are ever-increasing and there are many challenges that ne...
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
ABSTRACTIn the general population and in heart disease, pulmonary hypertension (PH) is a strong and independent risk factor for mortality and adverse cardiovascular outcomes. We performed a systematic review and meta ‐analysis of longitudinal cohort studies of individuals with chronic kidney disease (CKD) of any‐stage (also including end‐stage kidney disease –ESKD‐ and kidney transplantation) stratified according to presence/absence of PH.18 eligible studies (10740 participants) were retrieved. PH had an overall pooled prevalence (PP) of 33% (95% CI 28 ‐42) and portended a higher risk of all‐cause mortali...
Source: Therapeutic Apheresis and Dialysis - Category: Hematology Authors: Tags: Review Source Type: research
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Source: Blood - Category: Hematology Authors: Tags: 634. Myeloproliferative Syndromes: Clinical: Poster III Source Type: research
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Source: Blood - Category: Hematology Authors: Tags: 903. Outcomes Research-Non-Malignant Hematology: Poster II Source Type: research
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Source: Blood - Category: Hematology Authors: Tags: 904. Outcomes Research-Malignant Conditions: Real World Outcomes Source Type: research
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Source: Australian Health Review - Category: Hospital Management Authors: Tags: Aust Health Rev Source Type: research
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Source: PickTheBrain | Motivation and Self Improvement - Category: Consumer Health News Authors: Tags: featured health and fitness pickthebrain self improvement vitamins what vitamins should i take Source Type: blogs
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