AI can distinguish between types of spondylitis on MRI

An artificial intelligence (AI) algorithm can differentiate between tuberculous...Read more on AuntMinnie.comRelated Reading: AI can find, classify pleural effusions on chest x-rays AI algorithm predicts lung disease, adverse events on CT Can AI accurately diagnose tuberculosis from chest x-rays? CT lung screening finds cancer in nonsmokers Digital tomosynthesis works well for spinal tuberculosis
Source: Headlines - Category: Radiology Source Type: news

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CONCLUSION: Through a multidisciplinary initiative involving pharmacists, physicians, nurses, and leadership, a new process to promote the safe preparation and administration of the tuberculosis vaccine Mycobacterium bovis BCG was developed and implemented. The results of a post-implementation time study indicated that a standardized approach to scheduling, preparing, and administering BCG was effective in managing the operations of BCG through having high clinic and patient satisfaction. PMID: 30873517 [PubMed - as supplied by publisher]
Source: American Journal of Health-System Pharmacy : AJHP - Category: Drugs & Pharmacology Authors: Tags: Am J Health Syst Pharm Source Type: research
Publication date: Available online 14 March 2019Source: The LancetAuthor(s): Thomas J Bollyky, Tara Templin, Matthew Cohen, Diana Schoder, Joseph L Dieleman, Simon WigleySummaryBackgroundPrevious analyses of democracy and population health have focused on broad measures, such as life expectancy at birth and child and infant mortality, and have shown some contradictory results. We used a panel of data spanning 170 countries to assess the association between democracy and cause-specific mortality and explore the pathways connecting democratic rule to health gains.MethodsWe extracted cause-specific mortality and HIV-free life...
Source: The Lancet - Category: General Medicine Source Type: research
Authors: Fitzgerald DB, Leong SL, Budgeon CA, Murray K, Rosenstengal A, Smith NA, Bielsa S, Clive AO, Maskell NA, Porcel JM, Lee YCG Abstract Background: Pleural fluid pH and glucose levels are both recommended in the workup of pleural effusions. Whether their levels correlate and predict each other or contribute independent knowledge is unclear. We aimed to investigate the pH/glucose relationship, assess their concordance and ascertain whether performing both tests provides additional information to performing either test alone. Methods: The pH and glucose measurements from 2,971 pleural fluid samples, from th...
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
President Donald Trump’s proposed 2020 budget includes nearly $300 million meant to “defeat the HIV/AIDS epidemic” in the U.S. — even as it calls for a 12% reduction in total funding to the Department of Health and Human Services (HHS). During his February State of the Union address, Trump announced an ambitious plan to “eliminate the HIV epidemic in the United States within 10 years.” During a subsequent call with reporters, health officials said the initiative would focus on 48 at-risk counties across the country and would involve promoting early HIV treatment and diagnosis, expanding ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized HIV/AIDS Source Type: news
Abstract Very few adjuvants inducing Th1 immune response have been developed and are under clinical investigation. Hence, there is the need to find an adjuvant that elicits strong Th1 immune response which should be safe when injected in the host along with vaccines. Mycobacterium indicus pranii (MIP), a non-pathogenic vaccine candidate, has shown strong immunomodulatory activity in leprosy/tuberculosis/cancer and in genital warts patients where its administration shifted the host immune response towards Th1 type. These findings prompted us to study the components of MIP in detail for their Th1 inducing property. ...
Source: International Immunopharmacology - Category: Allergy & Immunology Authors: Tags: Int Immunopharmacol Source Type: research
We present a case of a 22-year-old man with history of allogenic renal transplantation on immunosuppression, who underwent 18F-FDG-PET/CT to characterize a lesion in the transplanted kidney on ultrasonogram and contrast-enhanced computed tomography imaging. PET/CT revealed FDG avid lesion in the transplanted kidney and mural thickening involving the distal ileum, ileocecal junction, and ileocolic lymph nodes. Subsequent histopathological examination from the renal lesion revealed renal cell carcinoma in the transplanted kidney. Additionally, endoscopic biopsy from the ileal thickening revealed granulomatous inflammation, s...
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Interesting Images Source Type: research
Mycobacterium bovis Bacille Calmette-Gu érin (BCG) is not only used as a vaccine against tuberculosis but also protects against leprosy and is used as part of bladder cancer treatment to induce a protective immune...
Source: Microbial Cell Factories - Category: Microbiology Authors: Tags: RESEARCH Source Type: research
Authors: Kubota M, Suzuki J, Morisawa Y PMID: 30828043 [PubMed - in process]
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
CONCLUSION: Bioisosteric replacement of 1,3-diketo functional group in hispolons with pyrazole or isoxazole rings have resulted in potent anti TB molecules. Docking simulations of these compounds on mtFabH enzyme resulted in clear understanding on bioactivity profiles of these compounds. Docking scores are in good agreement with the anti TB activity obtained for these compounds. Computational studies and in vitro screening results are indicating at mtFabH as the probable target for these compounds. PMID: 30834836 [PubMed - as supplied by publisher]
Source: Current Topics in Medicinal Chemistry - Category: Chemistry Authors: Tags: Curr Top Med Chem Source Type: research
The health effects of short-term exposure to air pollutants on respiratory deaths and its modifiers such as meteorological indexes have been widely investigated. However, most of the previous studies are limited to single pollutants or total respiratory deaths, and their findings are inconsistent. To comprehensively examine the short-term effects of air pollutants on daily respiratory mortality. Our analysis included 16,931 nonaccidental respiratory deaths (except lung cancer and tuberculosis) among older adults (>65 years) from 2011 to 2017 in Jinan, China. We used a generalized additive Poisson models adjusted for m...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
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