Palmitoylethanolamide counteracts autistic-like behaviours in BTBR T+tf/J mice: contribution of central and peripheral mechanisms.

In conclusion, our results demonstrated a therapeutic potential of PEA in limiting ASD symptoms, through its pleiotropic mechanism of action, supporting neuroprotection, anti-inflammatory effects, and the modulation of gut-brain axis.
PMID: 30193877 [PubMed - as supplied by publisher]

Source: Brain, Behavior, and Immunity - September 4, 2018 Category: Neurology Authors: Cristiano C, Pirozzi C, Coretti L, Cavaliere G, Lama A, Russo R, Lembo F, Pina Mollica M, Meli R, Calignano A, Mattace Raso G Tags: Brain Behav Immun Source Type: research