Painful Oral Lesions.
Painful Oral Lesions. Dent Clin North Am. 2018 Oct;62(4):597-609 Authors: Hargitai IA Abstract Painful oral vesiculoerosive diseases (OVD) include lichen planus, pemphigus vulgaris, mucous membrane pemphigoid, erythema multiforme, and recurrent aphthous stomatitis. OVD lesions have an immunopathic cause. Treatment is aimed at reducing the immunologic and the following inflammatory response. The mainstay of OVD management is topical or systemic corticosteroids to include topical triamcinolone, fluocinonide, and clobetasol, whereas systemic medications used in practice can include dexamethasone, prednisone, and prednisolone. Oral herpetic lesions can be primary or recurrent. If management is desired, they can be treated by topical or systemic antiviral drugs. Topical antiviral creams include prescription acyclovir, penciclovir and over-the-counter docosanol. PMID: 30189985 [PubMed - in process]
Publication date: Available online 28 January 2020Source: Journal of OrthopaedicsAuthor(s): Bura Sindhupakorn, Darawan Jomkoh, Theeranit NamkunteeAbstractBackgroundCorticosteroid and Ketorolac tromethamine is a pain reducing.ObjectiveThe primary objective was pain intensity scores (VAS) in 10, 30, 60 minutes, 2, 6 hours, 1, and 7 days.Method120 patients were randomized. The placebo group (normal saline) and experimental groups (ketorolac 30 mg, 60 mg, triamcinolone 10 mg, 20 mg., and 40 mg, respectively) were compared.ResultVAS at 60 min, 2, 6 hours, 1 and 7 days was significantly different (P
ConclusionChronic preoperative steroid is not a significant risk factor for surgical site infection following rTKA, but it is independently associated with increased risk of septic shock and prolonged hospital length of stay.
Publication date: February 2020Source: JACC: Heart Failure, Volume 8, Issue 2Author(s): Chao Liu, Kunshen Liu
Publication date: February 2020Source: JACC: Heart Failure, Volume 8, Issue 2Author(s): Òscar Miró, Koji Takagi, Pere Llorens, Alexandre Mebazaa
Publication date: Available online 26 December 2019Source: Clinical Lymphoma Myeloma and LeukemiaAuthor(s): Meghan Salcedo, Nikoletta Lendvai, Donna Mastey, Julia Schlossman, Malin Hultcrantz, Neha Korde, Sham Mailankody, Alexander Lesokhin, Hani Hassoun, Eric Smith, Urvi Shah, Victoria Diab, Kelly Werner, Heather Landau, Oscar Lahoud, Pamela Drullinsky, Gunjan Shah, David Chung, Michael Scordo, Sergio Giralt
Condition: Multiple Myeloma Intervention: Drug: Pomalidomide + Cyclophosphamide + Dexamethasone Sponsor: Maimónides Biomedical Research Institute of Córdoba Terminated
Publication date: Available online 28 January 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Gayatri B. Patel, Robert C. Kern, Jonathan A. Bernstein, Park Hae-Sim, Anju T. PetersAdvances in understanding the pathogenic mechanisms of both rhinitis and chronic rhinosinusitis have resulted in new treatment options, especially for chronic rhinosinusitis. A review of relevant medical and surgical clinical studies shows that intranasal corticosteroids, antihistamines, and allergen immunotherapy continue to be the best treatments for chronic rhinitis. Dupilumab is the first biologic approved for...
CONCLUSION: Myocarditis occurring during ICI treatment is a rare but potentially lethal event. Daily serum troponin level seems to predict ICI-related myocarditis but interpretation could be difficult in the context of associated myositis. Echocardiography and cardiac MRI are also useful but can remain negative. Electrocardiogram is a cornerstone of myocarditis diagnosis. In case of cardiac involvement, continuous heart rhythm monitoring should be performed in addition to the administration of high-dose corticosteroids therapy and the cessation of ICI therapy. Add-on treatments should be discussed with a well-trained multi...
Are asthma patients who use inhaled corticosteroids at an increased risk for pneumonia and hospitalization?BMC Pulmonary Medicine
A short course of a potent dose of prednisolone safely reduced finger pain and local joint inflammation in patients with hand osteoarthritis, a trial in The Lancet reported.