Diagnostic Accuracy of a Precision Medicine Blood Test for Assessing Obstructive Coronary Artery Disease in Nondiabetic Patients with Newly-Diagnosed Heart Failure with Reduced Ejection Fraction - A Pilot Study

In patients with newly-diagnosed heart failure with reduced ejection fraction (HFrEF), current guidelines recommend ischemic workup to rule out the presence of coronary artery disease (CAD), as revascularization in patients with left ventricular systolic dysfunction associated with obstructive CAD is strongly associated with improved survival. This ischemic work-up is based initially on non-invasive testing and, if indicated, invasive coronary angiography (ICA). While non-invasive testing is limited by its low diagnostic yield, ICA exposes patients to radiation, IV contrast and procedural complications.
Source: Journal of Cardiac Failure - Category: Cardiology Authors: Tags: 006 Source Type: research