Specific Pro-Inflammatory Signaling Pathways are Induced in Patients with Cardiac Sarcoidosis; Potential Prognostic/Therapeutic Applications

While cardiac imaging has improved the diagnosis and risk assessment for cardiac sarcoidosis, treatment regimens have consisted of generalized heart failure (HF) therapies and non-specific anti-inflammatory regimens. Thus, improvements in identifying the relative progression of this cardiovascular condition as well as identifying more specific therapeutic targets are necessary. The overall goal of this study was to perform high sensitivity plasma profiling of specific inflammatory pathways in patients with suspected cardiac sarcoidosis.

Source: Journal of Cardiac Failure - August 1, 2018 Category: Cardiology Authors: Bryan Young, Kelsie E. Oatmen, Lisa A. Freeburg, Kia N. Zellars, Ashley A. Sapp, Erica Herzog, Edward J. Miller, Francis G. Spinale Tags: 020 Source Type: research