Evolution of Asymptomatic Left Ventricular Dysfunction in 380 Long-term Survivors of Childhood Cancer

Long-term childhood cancer survivors (CCS) treated with cardiotoxic cancer therapies (CTCT) are screened for LV dysfunction (LVD). The intervals of 2 to 5 years in the Dutch Childhood Oncology Group guideline (Annals of Oncology 2012) depend on anthracycline (300 mg/m2) and radiotherapy dose (30 Gy). There is a gap between detection of LVD, defined as an ejection fraction (EF)

Source: Journal of Cardiac Failure - August 1, 2018 Category: Cardiology Authors: Jan M. Leerink, Heleen J.H. Van Der Pal, Elizabeth A.M. Feijen, Paola G. Meregalli, Yigal M. Pinto, Leontien C.M. Kremer, Wouter E.M. Kok Tags: 030 Source Type: research