The putative tumour suppressor miR-1-3p modulates prostate cancer cell aggressiveness by repressing E2F5 and PFTK1.

CONCLUSION: These data highlight an important role for miR-1-3p in the regulation of proliferation and cell cycle in the molecular etiology of PCa and indicate the potential for miR-1-3p in applications furthering PCa prognostics and therapeutics. PMID: 30185212 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/30185212?dopt=Abstract

Source: Clinical Prostate Cancer - September 5, 2018 Category: Cancer & Oncology Authors: Li SM, Wu HL, Yu X, Tang K, Wang SG, Ye ZQ, Hu J Tags: J Exp Clin Cancer Res Source Type: research