Immunohistochemical analysis of spinal cord components in mouse model of experimental autoimmune encephalomyelitis.

CONCLUSIONS: In mouse model of EAE, inflammatory cells predominate in the early phases of the disease. This study shows for the first time that inflammation precedes oligodendrocyte death and neuronal loss and that macrophages/ microglia are the only cells persisting in large numbers in the chronic phase of the disease, probably because of the switch from proinflammatory to anti-inflammatory phenotype. PMID: 30187907 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30187907?dopt=Abstract

Source: Folia Histochemica et Cytobiologica - September 8, 2018 Category: Cytology Tags: Folia Histochem Cytobiol Source Type: research